Probing cellular events, one quantum dot at a time

F Pinaud, S Clarke, A Sittner, M Dahan - Nature methods, 2010 - nature.com
Monitoring the behavior of single molecules in living cells is a powerful approach to
investigate the details of cellular processes. Owing to their optical, chemical and …

Ligand-bound quantum dot probes for studying the molecular scale dynamics of receptor endocytic trafficking in live cells

SS Rajan, HY Liu, TQ Vu - ACS nano, 2008 - ACS Publications
Endocytic receptor trafficking is a complex, dynamic process underlying fundamental cell
function. An integrated understanding of endocytosis at the level of single or small numbers …

Quantum dots for quantitative imaging: from single molecules to tissue

TQ Vu, WY Lam, EW Hatch, DS Lidke - Cell and tissue research, 2015 - Springer
Since their introduction to biological imaging, quantum dots (QDs) have progressed from a
little known, but attractive, technology to one that has gained broad application in many …

Compact and blinking-suppressed quantum dots for single-particle tracking in live cells

LA Lane, AM Smith, T Lian, S Nie - The Journal of Physical …, 2014 - ACS Publications
Quantum dots (QDs) offer distinct advantages over organic dyes and fluorescent proteins for
biological imaging applications because of their brightness, photostability, and tunability …

Next-generation quantum dots

AM Smith, S Nie - Nature biotechnology, 2009 - nature.com
Next-generation quantum dots | Nature Biotechnology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Efficient delivery of quantum dots into the cytosol of cells using cell-penetrating poly (disulfide) s

E Derivery, E Bartolami, S Matile… - Journal of the …, 2017 - ACS Publications
Quantum dots (QDs) are extremely bright, photostable, nanometer particles broadly used to
investigate single molecule dynamics in vitro. However, the use of QDs in vivo to investigate …

Quantum dot applications to neuroscience: new tools for probing neurons and glia

S Pathak, E Cao, MC Davidson, S Jin… - Journal of …, 2006 - Soc Neuroscience
Semiconductor fluorescent quantum dots are nanometer-sized functionalized particles that
display unique physical properties that make them particularly well suited for visualizing and …

Quantum dots for live cells, in vivo imaging, and diagnostics

X Michalet, FF Pinaud, LA Bentolila, JM Tsay, S Doose… - science, 2005 - science.org
Research on fluorescent semiconductor nanocrystals (also known as quantum dots or
qdots) has evolved over the past two decades from electronic materials science to biological …

Mechanochemical delivery and dynamic tracking of fluorescent quantum dots in the cytoplasm and nucleus of living cells

K Yum, S Na, Y Xiang, N Wang, MF Yu - Nano letters, 2009 - ACS Publications
Studying molecular dynamics inside living cells is a major but highly rewarding challenge in
cell biology. We present a nanoscale mechanochemical method to deliver fluorescent …

Semiconductor quantum dots for in vitro diagnostics and cellular imaging

Z Jin, N Hildebrandt - Trends in biotechnology, 2012 - cell.com
The need for companion diagnostics, point-of-care testing (POCT) and high-throughput
screening in clinical diagnostics and personalized medicine has pushed the need for more …