To date, endoscopic remission is the main therapeutic target in patients with ulcerative colitis
(UC), influencing treatment decisions. 1 However, growing evidence shows that subjects …

We read with great interest the editorial:“Endoscopy and histology in inflammatory bowel
disease patients: complementary or alternatives?” 1 and we thank Dr. D'Amico et al. for …

The management of inflammatory bowel disease (IBD) is based increasingly on the
objective assessment of inflammation and mucosal integrity. It has been shown that …

Endoscopy plays a vital role in the diagnosis, monitoring, and surveillance of UC, with the
ultimate goal of achieving endoscopic remission as a treatment target. The significance of …

Histology is a treatment target for investigational agents. Histologic activity predicts relapses
and increased risk of colorectal neoplasia. Recent studies demonstrated that the proportion …

Diagnosis of ulcerative colitis (UC) or Crohn's disease (CD) relies on the combination of
clinical, laboratory, and endoscopic data, which are needed for diagnosis according to adult …

Since the development of the “treat to target” and “mucosal healing” concepts, the treatment
goal for patients with UC has changed. Before the mucosal healing concept emerged, the …

Background Endoscopy is routinely performed in patients with inflammatory bowel disease
to evaluate disease severity and guide important clinical decisions. However, variability in …

For many decades, the treatment goal in ulcerative colitis (UC) has been clinical remission,
defined as a complete resolution of symptoms. Though it is still not standard of care, in …

Crohn's disease (CD) as “the treatment of symptoms.” This was in contrast to the treatment of
ulcerative colitis (UC), where clinical trials had discriminated between “induction of …