Epidemiological and biological plausibility studies support a cause-and-effect relationship
between increased levels of physical activity or cardiorespiratory fitness and reduced …

Abstract Purpose of review The “Extreme Exercise Hypothesis” is characterized by a U-
shaped or reverse J-shaped, dose-response curve between physical activity volumes and …

Multiple epidemiological studies document that habitual physical activity reduces the risk of
atherosclerotic cardiovascular disease (ASCVD), and most demonstrate progressively lower …

Habitual physical activity reduces coronary heart disease events, but vigorous activity can
also acutely and transiently increase the risk of sudden cardiac death and acute myocardial …

Sports activity may precipitate acute fatalities in both adults and young competitive athletes
with concealed heart diseases. However, the risk-benefit ratio of physical exercise differs …

Habitual physical activity reduces coronary heart disease events, but vigorous activity can
also acutely and transiently increase the risk of sudden cardiac death and acute myocardial …

The association between physical activity and health was recognized as early as the fifth
century BC by the Greek physician Hippocrates, who wrote the following:“All parts of the …

Vigorous physical exercise may precipitate acute fatalities in both adults and young
competitive athletes with concealed heart diseases. However, the risk–benefit ratio of …

Exercise confers a plethora of health benefits that are well documented, whereas physical
inactivity is a leading risk factor for cardiovascular morbidity and mortality. The dose of …

It is widely accepted that regular physical activity is beneficial for cardiovascular health.
Frequent exercise is robustly associated with a decrease in cardiovascular mortality as well …