Vascular macrophages in atherosclerosis

H Xu, J Jiang, W Chen, W Li… - Journal of immunology …, 2019 - Wiley Online Library
Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

Macrophages and immune cells in atherosclerosis: recent advances and novel concepts

C Cochain, A Zernecke - Basic research in cardiology, 2015 - Springer
Atherosclerotic lesion-related thrombosis is the major cause of myocardial infarction and
stroke, which together constitute the leading cause of mortality worldwide. The inflammatory …

Macrophages heterogeneity in atherosclerosis–implications for therapy

HM Wilson - Journal of cellular and molecular medicine, 2010 - Wiley Online Library
Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …

Atherosclerosis and immunity: a perspective

F Abdolmaleki, SMG Hayat, V Bianconi… - Trends in cardiovascular …, 2019 - Elsevier
Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

The role of monocytes and macrophages in human atherosclerosis, plaque neoangiogenesis, and atherothrombosis

F Moroni, E Ammirati, GD Norata… - Mediators of …, 2019 - Wiley Online Library
Atherosclerosis is one of the leading causes of death and disability worldwide. It is a
complex disease characterized by lipid accumulation within the arterial wall, inflammation …

Macrophage phenotypes in atherosclerosis

S Colin, G Chinetti‐Gbaguidi, B Staels - Immunological reviews, 2014 - Wiley Online Library
Initiation and progression of atherosclerosis depend on local inflammation and
accumulation of lipids in the vascular wall. Although many cells are involved in the …

Macrophage plasticity and atherosclerosis therapy

P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

The role of macrophages in the pathogenesis of atherosclerosis

AV Blagov, AM Markin, AI Bogatyreva, TV Tolstik… - Cells, 2023 - mdpi.com
A wide variety of cell populations, including both immune and endothelial cells, participate in
the pathogenesis of atherosclerosis. Among these groups, macrophages deserve special …

Roles of macrophages in atherogenesis

L Farahi, SK Sinha, AJ Lusis - Frontiers in pharmacology, 2021 - frontiersin.org
Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Macrophage subsets in atherosclerosis

G Chinetti-Gbaguidi, S Colin, B Staels - Nature Reviews Cardiology, 2015 - nature.com
Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …