Humans commonly have low level antibodies to poly (ethylene) glycol (PEG) due to
environmental exposure. Lipid nanoparticle (LNP) mRNA vaccines for SARS-CoV-2 contain …

PEGylated lipids are one of the four constituents of lipid nanoparticle mRNA COVID-19
vaccines. Therefore, various concerns have been raised on the generation of anti-PEG …

The successful mRNA vaccines against COVID-19 contain polyethylene glycol (PEG) to
stabilize the lipid nanoparticles. Recent data show that PEG-specific antibodies can be …

The early and massive vaccination campaign in Israel with the mRNA-LNP
Comirnaty®(Pfizer-BioNTech) vaccine against the SARS-CoV-2 virus made available large …

Two messenger RNA (mRNA)-based vaccines are widely used globally to prevent
coronavirus disease 2019 (COVID-19). Both vaccine formulations contain PEGylated lipids …

Vaccines based on mRNA-containing lipid nanoparticles (LNPs) pioneered by Katalin
Karikó and Drew Weissman at the University of Pennsylvania are a promising new vaccine …

The spread of the SARS-CoV-2 into a global pandemic within a few months of onset
motivates the development of a rapidly scalable vaccine. Here, we present a self-amplifying …

Polyethylene glycol (PEG) is a flexible, hydrophilic simple polymer that is physically attached
to peptides, proteins, nucleic acids, liposomes, and nanoparticles to reduce renal clearance …

There is an urgent need for vaccines to counter the COVID-19 pandemic due to infections
with severe acute respiratory syndrome coronavirus (SARS-CoV-2). Evidence from …

Although allergic responses to the mRNA COVID-19 vaccines are rare, recent reports have
suggested that a small number of individuals with allergy to polyethylene glycol (PEG), a …