Comparative effectiveness of sotrovimab versus no treatment in non-hospitalised high-risk COVID-19 patients in north west London: a retrospective cohort study

M Drysdale, ER Galimov… - BMJ Open …, 2024 - bmjopenrespres.bmj.com
Background We assessed the effectiveness of sotrovimab vs no early COVID-19 treatment in
highest-risk COVID-19 patients during Omicron predominance. Methods Retrospective …

Comparative effectiveness of sotrovimab versus no treatment in non-hospitalised high-risk patients with COVID-19 in North West London: a retrospective cohort study …

M Drysdale, ER Galimov, MJ Yarwood, V Patel… - medRxiv, 2023 - medrxiv.org
Introduction: There is uncertainty regarding how in vitro antibody neutralisation activity
translates to the clinical efficacy of sotrovimab against severe acute respiratory syndrome …

Characteristics and outcomes of patients with COVID-19 at high-risk of disease progression receiving sotrovimab, oral antivirals or no treatment in England

V Patel, MJ Yarwood, B Levick, DC Gibbons… - medRxiv, 2022 - medrxiv.org
Introduction There is limited real-world evidence surrounding the effectiveness of early, mild-
to-moderate COVID-19 treatments following the emergence and dominance of Omicron …

[HTML][HTML] Characteristics and outcomes of COVID-19 patients presumed to be treated with sotrovimab in NHS hospitals in England

V Patel, B Levick, S Boult, DC Gibbons… - BMC Infectious …, 2024 - Springer
Background The impact of the constantly evolving severe acute respiratory syndrome
coronavirus 2 on the effectiveness of early coronavirus disease 2019 (COVID-19) treatments …

Effect of sotrovimab on hospitalization or death among high-risk patients with mild to moderate COVID-19: a randomized clinical trial

A Gupta, Y Gonzalez-Rojas, E Juarez, MC Casal… - Jama, 2022 - jamanetwork.com
Importance Older patients and those with comorbidities who are infected with SARS-CoV-2
may be at increased risk of hospitalization and death. Sotrovimab is a neutralizing antibody …

[HTML][HTML] Characteristics and outcomes of patients with COVID-19 at high risk of disease progression receiving sotrovimab, oral antivirals, or no treatment: a …

M Drysdale, H Tibble, V Patel, DC Gibbons… - BMC Infectious …, 2024 - Springer
Background The clinical benefit of coronavirus disease 2019 (COVID-19) treatments against
new circulating variants remains unclear. We sought to describe characteristics and clinical …

Characteristics and outcomes of patients treated with sotrovimab to prevent progression to severe COVID-19 in Belgium

M Drysdale, T Hautekiet, M Singh, J Hautekiet… - medRxiv, 2023 - medrxiv.org
Background Sotrovimab, a dual-action, engineered human monoclonal antibody, has been
demonstrated to significantly reduce the risk of hospitalization and death in high-risk patients …

[HTML][HTML] Real-world effectiveness of sotrovimab for the early treatment of COVID-19 during SARS-CoV-2 Delta and Omicron waves in the USA

MM Cheng, C Reyes, S Satram, H Birch… - Infectious diseases and …, 2023 - Springer
Introduction Sotrovimab, a recombinant human monoclonal antibody (mAb) against severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had US Food and Drug …

[HTML][HTML] Real-World Effectiveness of Sotrovimab for the Early Treatment of COVID-19: Evidence from the US National COVID Cohort Collaborative (N3C)

CF Bell, P Bobbili, R Desai, DC Gibbons… - Clinical Drug …, 2024 - Springer
Abstract Background and Objective The coronavirus disease 2019 (COVID-19) pandemic
has been an unprecedented healthcare crisis, one that threatened to overwhelm health …

[HTML][HTML] Change in effectiveness of sotrovimab for preventing hospitalization and mortality for at-risk COVID-19 outpatients during an Omicron BA. 1 and BA. 1.1 …

NR Aggarwal, LE Beaty, TD Bennett, NE Carlson… - International journal of …, 2023 - Elsevier
Objectives Sotrovimab effectively prevented progression to severe disease and mortality
following infection with pre-Omicron SARS-CoV-2 variants. We sought to determine whether …