Highlights•Cortical interneurons originate in the embryonic subcortical
telencephalon.•Spatial and temporal control of progenitor differentiation generates …

Highlights•The GEs produce many types of GABAergic projection neurons and a majority of
GABAergic interneurons.•Spatial origin, birthdate, and mode of division influence …

The proper construction of neural circuits requires the generation of diverse cell types, their
distribution to defined regions, and their specific and appropriate wiring. A major objective in …

The central goal of this manuscript is to survey our present knowledge of how cortical
interneuron subtypes are generated. To achieve this, we will first define what is meant by …

Previous work has demonstrated that the character of mouse cortical interneuron subtypes
can be directly related to their embryonic temporal and spatial origins. The relationship …

GABAergic interneurons influence the development and function of the cerebral cortex
through the actions of a variety of subtypes. Despite the relevance to cortical function and …

Most γ-aminobutyric acidergic interneurons in the neocortex and hippocampus are derived
from subpallial progenitors in the medial ganglionic eminence and migrate tangentially to …

At present little is known about the developmental mechanisms that give rise to inhibitory γ-
aminobutyric acidergic interneurons of the neocortex or the timing of their subtype …

Cerebral cortical functions are conducted by two general classes of neurons: glutamatergic
projection neurons and GABAergic interneurons. Distinct interneuron subtypes serve distinct …

GABA-containing interneurons are crucial to both the development and function of the
cerebral cortex. Unlike cortical projection neurons, which have a relatively conserved set of …