[HTML][HTML] Selenium in bodily homeostasis: hypothalamus, hormones, and highways of communication

P Toh, JL Nicholson, AM Vetter, MJ Berry… - International journal of …, 2022 - mdpi.com
The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

[HTML][HTML] Biological activity of selenium and its impact on human health

G Genchi, G Lauria, A Catalano, MS Sinicropi… - International journal of …, 2023 - mdpi.com
Selenium (Se) is a naturally occurring metalloid element essential to human and animal
health in trace amounts but it is harmful in excess. Se plays a substantial role in the …

Selenoproteins and their impact on human health through diverse physiological pathways

B Moghadaszadeh, AH Beggs - Physiology, 2006 - journals.physiology.org
In the last few decades, the importance of selenium in human health has been the subject of
numerous studies. It is believed that the physiological effects of selenium occur mainly …

Selenium in biology: facts and medical perspectives

J Köhrle, R Brigelius-Flohé, A Böck, R Gärtner… - 2000 - degruyter.com
Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …

[HTML][HTML] Selenium as an important factor in various disease states-a review

M Kieliszek, I Bano - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Selenium (Se) is an element that has a pro-health effect on humans and animals. However,
both the deficiency of this element and its excess may prove harmful to the body depending …

Selenium in human health and disease: An overview

R Brigelius-Flohé - Selenium, 2018 - Springer
Since its detection in 1817 selenium underwent an adventurous trip from a toxic to an
essential element. As integral part of selenoproteins it was assumed that it is capable to …

Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: the selenium paradox

KH Lee, D Jeong - Molecular medicine reports, 2012 - spandidos-publications.com
Selenium is an essential biological trace element. Adult daily intake of selenium should be
approximately 100 µg per day. This compound has a two-sided effect depending on its …

[HTML][HTML] The role and mechanism of essential selenoproteins for homeostasis

R Ye, J Huang, Z Wang, Y Chen, Y Dong - Antioxidants, 2022 - mdpi.com
Selenium (Se) is one of the essential trace elements that plays a biological role in the body,
mainly in the form of selenoproteins. Selenoproteins can be involved in the regulation of …

[HTML][HTML] Dietary selenium and selenoprotein function

BS Weeks, MS Hanna… - Medical science monitor …, 2012 - ncbi.nlm.nih.gov
Selenium is a trace mineral and an essential nutrient in the human diet. Selenium is found in
soil and water and consequently enters the food chain through the root ways of plants and …

Molecular actions of selenium in the brain: neuroprotective mechanisms of an essential trace element

AU Bräuer, NΕ Savaskan - Reviews in the Neurosciences, 2004 - degruyter.com
In addition to acting as an essential nutrient for the immune system and overall body
function, it is apparent that selenium also plays a critical role in the operation of the nervous …