A purified spike (S) glycoprotein of severe acute respiratory syndrome-related coronavirus 2
(SARS-CoV-2) coronavirus was used to study its effects on THP-1 macrophages, peripheral …

Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now spread globally. Some …

An understanding of the pathological inflammatory mechanisms involved in SARS-CoV-2
virus infection is necessary in order to discover new molecular pharmacological targets for …

Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2
infection, although the mechanism for initiation of a hyper-inflammatory response, and multi …

The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however,
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …

Although COVID-19 has become a major challenge to global health, there are currently no
efficacious agents for effective treatment. Cytokine storm syndrome (CSS) can lead to acute …

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has spread worldwide and has infected more than 250 million …

Mounting evidence accumulates that hematopoietic stem/progenitor cells (HSPCs) and
endothelial progenitor cells (EPCs) are damaged during severe SARS-Cov-2/COVID-19 …

The coronavirus disease 2019 (COVID-19) pandemic began in January 2020 in Wuhan,
China, with a new coronavirus designated SARS-CoV-2. The principal cause of death from …

Background SARS-CoV-2 infects through the respiratory route and triggers inflammatory
response by affecting multiple cell types including type II alveolar epithelial cells. SARS-CoV …