Pulmonary fibrosis: Therapeutic and mechanistic insights into the role of phytochemicals

SA Hosseini, F Zahedipour, T Sathyapalan… - …, 2021 - Wiley Online Library
Pulmonary fibrosis (PF) is the devastating consequence of various inflammatory diseases of
the lung. PF leads to a reduction of lung function, respiratory failure, and death. Several …

Natural product-based potential therapeutic interventions of pulmonary fibrosis

M Hasan, NC Paul, SK Paul, ASM Saikat, H Akter… - Molecules, 2022 - mdpi.com
Pulmonary fibrosis (PF) is a disease-refractive lung condition with an increased rate of
mortality. The potential factors causing PF include viral infections, radiation exposure, and …

The role of natural products in the prevention and treatment of pulmonary fibrosis: a review

L Wang, S Li, Y Yao, W Yin, T Ye - Food & function, 2021 - pubs.rsc.org
Pulmonary fibrosis is an incurable end-stage lung disease and remains a global public
health problem. Although there have been some breakthroughs in understanding the …

The efficacy of plant extract and bioactive compounds approaches in the treatment of pulmonary fibrosis: A systematic review

S Bahri, RB Ali, A Abidi, S Jameleddine - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Pulmonary fibrosis (PF) is a lethal, chronic and progressive respiratory disease leading to
interstitial lung damage and serious breathing problems. The pathogenic mechanism …

A standardized herbal extract PM014 ameliorates pulmonary fibrosis by suppressing the TGF-β1 pathway

KH Kim, S Lee, H Lee, D Shin, D Min, M Kim, B Ryu… - Scientific reports, 2018 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a devastating and common chronic lung disease
pathologically characterized by loss of epithelial cells and activation of fibroblasts and …

Polyphenols from Chinese herbal medicine: Molecular mechanisms and therapeutic targets in pulmonary fibrosis

L Wang, T Zhu, D Feng, R Li, C Zhang - The American Journal of …, 2022 - World Scientific
Pulmonary fibrosis (PF) is a highly confounding and fatal pathological process with finite
treatment options. Multiple factors such as oxidative and immune/inflammation involve key …

Natural plant resource flavonoids as potential therapeutic drugs for pulmonary fibrosis

MC Wang - Heliyon, 2023 - cell.com
Pulmonary fibrosis is an enduring and advancing pulmonary interstitial disease caused by
multiple factors that ultimately lead to structural changes in normal lung tissue. Currently …

Chinese medicine as a therapeutic option for pulmonary fibrosis: clinical efficacies and underlying mechanisms

Y Hao, J Li, L Dan, X Wu, X Xiao, H Yang… - Journal of …, 2023 - Elsevier
Ethnic pharmacological relevance Pulmonary fibrosis (PF) is a fibrotic interstitial lung
disease caused by continuous damage and excessive repair of alveolar epithelial cells, the …

Ferulic acid ameliorates the progression of pulmonary fibrosis via inhibition of TGF-β/smad signalling

SA Ali, MA Saifi, G Pulivendala, C Godugu… - Food and Chemical …, 2021 - Elsevier
Natural products are one of the best sources for the discovery of novel drugs and
compounds for multiple diseases. Pulmonary fibrosis (PF) is a chronic, progressive …

Current advances in idiopathic pulmonary fibrosis: the pathogenesis, therapeutic strategies and candidate molecules

M Lv, Y Liu, S Ma, Z Yu - Future medicinal chemistry, 2019 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a type of chronic, progressive lung disease with
unknown cause, which is characterized by increasing dyspnea and destruction of lung …