Given the increasing prevalence of end-stage kidney disease, the high morbidity and
mortality of dialysis treatment, and the shortage of donor kidneys, the field of nephrology is …

Decades of research into the molecular and cellular regulation of kidney morphogenesis in
rodent models, particularly the mouse, has provided both an atlas of the mammalian kidney …

The treatment of renal failure has seen little change in the past 70 years. Patients with end-
stage renal disease (ESRD) are treated with renal replacement therapy, including dialysis or …

Kidney diseases are a of major health problem worldwide. Despite advances in drug
therapies, they are only capable of slowing the progression of kidney diseases. Accordingly …

The ability to generate 3-dimensional models of the developing human kidney via the
directed differentiation of pluripotent stem cells—termed kidney organoids—has been hailed …

Background: With the rate of kidney disease on the rise, and a serious imbalance between
the number of patients requiring a kidney transplant and the number of available donor …

Kidney regeneration is likely to provide an inexhaustible source of tissues and organs for
immunosuppression‐free transplantation. It is currently garnering considerable attention and …

Chronic kidney disease (CKD) is a global health problem; the growing gap between the
number of patients awaiting transplant and organs actually transplanted highlights the need …

Despite a continuing increase in the number of patients suffering from chronic kidney
disease, currently available treatments for these patients, such as dialysis and kidney …

Investigations into bioengineering kidneys have been extensively conducted owing to their
potential for preclinical assays and regenerative medicine. Various approaches and …