Drug combinations for inhalation: Current products and future development addressing disease control and patient compliance

H Banat, R Ambrus, I Csóka - International Journal of Pharmaceutics, 2023 - Elsevier
Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

Pulmonary drug delivery: advances and challenges

A Nokhodchi, GP Martin - 2015 - books.google.com
Drug therapy via inhalation route is at the cutting edge of modern drug delivery research.
There has been significant progress on the understanding of drug therapy via inhalation …

Formulation technology to repurpose drugs for inhalation delivery

DC Cipolla, I Gonda - Drug Discovery Today: Therapeutic Strategies, 2011 - Elsevier
Inhalation of drugs for both medicinal and recreational purposes has occurred for centuries.
Over the last two decades, a variety of new formulation technologies and inhaler devices …

Improving inhaler technique, adherence to therapy and the precision of dosing: major challenges for pulmonary drug delivery

S Newman - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: The inhaled route has many advantages, but requires the patient to use, and to
master the use of, an inhaler device. Poor inhaler technique and non-adherence to therapy …

Inhalation delivery of complex drugs—the next steps

W de Kruijf, C Ehrhardt - Current opinion in pharmacology, 2017 - Elsevier
Highlights•Inhalation offers the opportunity to deliver complex molecules locally and
systemically.•Pulmonary insulin works well, but failed to make a commercial impact so …

Advances in inhaled technologies: understanding the therapeutic challenge, predicting clinical performance, and designing the optimal inhaled product

P Bäckman, H Adelmann, G Petersson… - Clinical …, 2014 - Wiley Online Library
Inhaled medicines are designed mainly to provide safe and efficacious treatment of
respiratory diseases, offering the potential advantages of targeted drug delivery such as …

Will pulmonary drug delivery for systemic application ever fulfill its rich promise?

D Cipolla - Expert opinion on drug delivery, 2016 - Taylor & Francis
While oral delivery of tablets and capsules remains the preferred treatment modality for most
patients, inhaled therapeutics have dominated the landscape for managing many common …

Pulmonary drug delivery system: Newer patents

SS Kaur - Pharmaceutical patent analyst, 2017 - Taylor & Francis
Inhalational route for drug delivery and desired effects has been known since centuries. This
lung-targeted therapy has benefited asthmatics and those with chronic respiratory problems …

Industry guidance for the selection of a delivery system for the development of novel respiratory products

JN Pritchard - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Respiratory diseases remain a target for improved forms of inhalation therapy.
However, there are neither regulatory preferences for one type of device over another, nor …

New inhaler devices-the good, the bad and the ugly

F Lavorini, GA Fontana, OS Usmani - Respiration, 2014 - karger.com
Drug delivery to the lungs is an effective way of targeting inhaled therapeutic aerosols and
treating obstructive airway diseases, such as asthma and chronic obstructive pulmonary …