Coronary microvascular dysfunction in diabetes mellitus: pathogenetic mechanisms and potential therapeutic options

T Salvatore, R Galiero, A Caturano, E Vetrano… - Biomedicines, 2022 - mdpi.com
Diabetic patients are frequently affected by coronary microvascular dysfunction (CMD), a
condition consisting of a combination of altered vasomotion and long-term structural change …

[HTML][HTML] Coronary microvascular dysfunction in diabetes mellitus: a review

A Picchi, S Capobianco, T Qiu, M Focardi… - World journal of …, 2010 - ncbi.nlm.nih.gov
The exploration of coronary microcirculatory dysfunction in diabetes has accelerated in
recent years. Cardiac function is compromised in diabetes. Diabetic patients manifest …

The pathogenic role of coronary microvascular dysfunction in the setting of other cardiac or systemic conditions

RE Konst, TJ Guzik, JC Kaski… - Cardiovascular …, 2020 - academic.oup.com
Coronary microvascular dysfunction (CMD) plays a pathogenic role in cardiac and systemic
conditions other than microvascular angina. In this review, we provide an overview of the …

Coronary microvascular dysfunction in diabetes mellitus

A Kibel, K Selthofer-Relatic… - Journal of …, 2017 - journals.sagepub.com
The significance, mechanisms and consequences of coronary microvascular dysfunction
associated with diabetes mellitus are topics into which we have insufficient insight at this …

Coronary microvascular dysfunction

S Godo, A Suda, J Takahashi, S Yasuda… - … , and vascular biology, 2021 - Am Heart Assoc
Over the past couple of decades, accumulating evidence has shown that structural and
functional abnormalities of coronary microvasculature are highly prevalent, associated with …

Coronary microvascular dysfunction: a review of recent progress and clinical implications

R Rehan, A Yong, M Ng, J Weaver… - Frontiers in …, 2023 - frontiersin.org
The coronary microcirculation plays a cardinal role in regulating coronary blood flow to meet
the changing metabolic demands of the myocardium. Coronary microvascular dysfunction …

Pathophysiology of coronary microvascular dysfunction

F Crea, RA Montone, R Rinaldi - Circulation Journal, 2022 - jstage.jst.go.jp
Ischemic heart disease (IHD) is commonly recognized as the consequence of coronary
atherosclerosis and obstructive coronary artery disease (CAD). However, a significant …

Coronary Microvascular Dysfunction Across the Spectrum of Cardiovascular Diseases: JACC State-of-the-Art Review

MG Del Buono, RA Montone, M Camilli… - Journal of the American …, 2021 - jacc.org
Coronary microvascular dysfunction (CMD) encompasses several pathogenetic
mechanisms involving coronary microcirculation and plays a major role in determining …

Coronary microvascular disease as an early culprit in the pathophysiology of diabetes and metabolic syndrome

H Labazi, AJ Trask - Pharmacological research, 2017 - Elsevier
Metabolic syndrome (MetS) is a group of cardio-metabolic risk factors that includes obesity,
insulin resistance, hypertension, and dyslipidemia; these are also a combination of …

Role of microangiopathy in diabetic cardiomyopathy

A Adameova, NS Dhalla - Heart failure reviews, 2014 - Springer
Although heart disease due to diabetes is mainly associated with complications of the large
vessels, microvascular abnormalities are also considered to be involved in altering cardiac …