The STEAP protein family: versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions
The human six‐transmembrane epithelial antigen of the prostate (STEAP) protein family
contains at least five homologous members. The necessity of multiple homologous STEAP …
contains at least five homologous members. The necessity of multiple homologous STEAP …
STEAP proteins: from structure to applications in cancer therapy
The human 6-transmembrane epithelial antigen of prostate (STEAP) family comprises
STEAP1, STEAP2, STEAP3, and STEAP4. All of these proteins are unique to mammals and …
STEAP1, STEAP2, STEAP3, and STEAP4. All of these proteins are unique to mammals and …
Six-Transmembrane Epithelial Antigen of Prostate 1 (STEAP1) Has a Single b Heme and Is Capable of Reducing Metal Ion Complexes and Oxygen
STEAP1, six-transmembrane epithelial antigen of prostate member 1, is strongly expressed
in several types of cancer cells, particularly in prostate cancer, and inhibition of its …
in several types of cancer cells, particularly in prostate cancer, and inhibition of its …
Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1)
W Oosterheert, P Gros - Journal of Biological Chemistry, 2020 - ASBMB
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane
protein that is highly up-regulated on the cell surface of several human cancers, making it a …
protein that is highly up-regulated on the cell surface of several human cancers, making it a …
STEAP1–4 (six-transmembrane epithelial antigen of the prostate 1–4) and their clinical implications for prostate cancer
Simple Summary Despite recent therapeutic advances in the treatment of prostate cancer,
metastatic castration-resistant prostate cancer continues to cause significant morbidity and …
metastatic castration-resistant prostate cancer continues to cause significant morbidity and …
Regulatory roles of six-transmembrane epithelial antigen of the prostate family members in the occurrence and development of malignant tumors
WJ Chen, HT Wu, CL Li, YK Lin, ZX Fang… - Frontiers in Cell and …, 2021 - frontiersin.org
The human six-transmembrane epithelial antigen of the prostate (STEAP) proteins, which
include STEAP1–4 and atypical STEAP1B, contain six transmembrane domains and are …
include STEAP1–4 and atypical STEAP1B, contain six transmembrane domains and are …
STEAP1 is overexpressed in cancers: a promising therapeutic target
J Moreaux, A Kassambara, D Hose, B Klein - Biochemical and biophysical …, 2012 - Elsevier
The six-transmembrane epithelial antigen of prostate (STEAP) protein was identified in
advanced prostate cancer and is up-regulated in multiple cancer cell lines, including …
advanced prostate cancer and is up-regulated in multiple cancer cell lines, including …
[HTML][HTML] Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate
KP Porkka, MA Helenius, T Visakorpi - Laboratory investigation, 2002 - Elsevier
By using subtraction and cDNA array hybridizations, we recently identified an anonymous
transcript that was differentially expressed in benign prostate hyperplasia and prostate …
transcript that was differentially expressed in benign prostate hyperplasia and prostate …
STEAP1 is over-expressed in breast cancer and down-regulated by 17β-estradiol in MCF-7 cells and in the rat mammary gland
Six transmembrane epithelial antigen of the prostate 1 (STEAP1) was identified as a
prostate-specific cell-surface antigen over-expressed in prostate cancer, and in human …
prostate-specific cell-surface antigen over-expressed in prostate cancer, and in human …
Targeting STEAP1 protein in human cancer: current trends and future challenges
J Barroca-Ferreira, JP Pais, MM Santos… - Current cancer drug …, 2018 - ingentaconnect.com
Cancer is a global health issue that impairs the life quality of patients and origins thousands
of deaths annually worldwide. Six-transmembrane epithelial antigen of the prostate …
of deaths annually worldwide. Six-transmembrane epithelial antigen of the prostate …