Thiosemicarbazone (s)-anchored water soluble mono-and bimetallic Cu (II) complexes: Enzyme-like activities, biomolecular interactions, anticancer property and real …

N Balakrishnan, J Haribabu, AK Dhanabalan… - Dalton …, 2020 - pubs.rsc.org
The reactions of CuCl2· 2H2O with chromone thiosemicarbazone ligands containing a–H or–
CH3 substituent on terminal N yielded monometallic Cu (II) complexes [Cu (HL1) Cl2](1) and …

Thiosemicarbazone Cu (II) and Zn (II) complexes as potential anticancer agents: Syntheses, crystal structure, DNA cleavage, cytotoxicity and apoptosis induction …

J Shao, ZY Ma, A Li, YH Liu, CZ Xie, ZY Qiang… - Journal of Inorganic …, 2014 - Elsevier
Four novel thiosemicarbazone metal complexes,[Cu (Am4M)(OAc)]· H 2 O (1),[Zn (HAm4M)
Cl 2](2),[Zn 2 (Am4M) 2 Br 2](3) and [Zn 2 (Am4M) 2 (OAc) 2]· 2MeOH (4)[HAm4M=(Z)-2 …

Designing anticancer copper (II) complexes by optimizing 2-pyridine-thiosemicarbazone ligands

J Deng, P Yu, Z Zhang, J Wang, J Cai, N Wu… - European Journal of …, 2018 - Elsevier
To develop potential next-generation metal anticancer agents, we designed and
synthesised five Cu (II) 2-pyridine-thiosemicarbazone complexes by modifying the hydrogen …

[HTML][HTML] Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest

D Mahendiran, S Amuthakala, NSP Bhuvanesh… - RSC …, 2018 - pubs.rsc.org
A series of six new bis (thiosemicarbazone) copper (I) complexes of the type [Cu (L1–6)
2Cl](1–6) have been synthesized and characterized. The molecular structure of the ligand …

A multifunctional molecular entity Cu II–Sn IV heterobimetallic complex as a potential cancer chemotherapeutic agent: DNA binding/cleavage, SOD mimetic …

S Tabassum, A Asim, RA Khan, F Arjmand… - RSC Advances, 2015 - pubs.rsc.org
New chiral L-valine-derived Schiff base complexes with the bioactive heterocyclic ligand
scaffold pyrazole (Hpz) were designed and synthesized with a view to find their potential as …

Antiproliferative activity of cationic and neutral thiosemicarbazone copper (II) complexes

MM Subarkhan, RN Prabhu, RR Kumar, R Ramesh - RSC advances, 2016 - pubs.rsc.org
The copper (II) complexes,[Cu (tscpy)(MeOH)](Cl)(1),[CuCl (mtscpy)](2) and [CuCl
(ptscpy)](3)(where, Htscpy= pyridoxal thiosemicarbazone, Hmtscpy= pyridoxal N4-methyl …

Mixed ligand copper (II)-diimine complexes of 2-formylpyridine-N 4-phenylthiosemicarbazone: Diimine co-ligands tune the in vitro nanomolar cytotoxicity

R Kartikeyan, D Murugan, T Ajaykamal… - Dalton …, 2023 - pubs.rsc.org
Recently, mixed-ligand copper (II) complexes have received much attention in searching for
alternative metallodrugs to cisplatin. A series of mixed ligand Cu (II) complexes of the type …

Synthesis, characterization, and in vitro anticancer activity of copper and zinc bis (thiosemicarbazone) complexes

R Anjum, D Palanimuthu, DS Kalinowski… - Inorganic …, 2019 - ACS Publications
A series of eight bis (thiosemicarbazone) ligands and 16 of their respective copper (II) and
zinc (II) complexes containing a combination of hydrogen, methyl, pyridyl, phenyl, and/or …

[HTML][HTML] Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu (I/II) complexes of thiosemicarbazone: special emphasis on their interactions with DNA

A Chakraborty, SP Dash, AK Panda, R Acharyya… - Dalton …, 2015 - pubs.rsc.org
4-(pX-phenyl) thiosemicarbazone of napthaldehyde {where X= Cl (HL1) and X= Br (HL2)},
thiosemicarbazone of quinoline-2-carbaldehyde (HL3) and 4-(p-fluorophenyl) …

Synthesis, characterization and biological activity of copper complexes with pyridoxal thiosemicarbazone derivatives. X-ray crystal structure of three dimeric …

MB Ferrari, F Bisceglie, G Pelosi, P Tarasconi… - Journal of inorganic …, 2004 - Elsevier
A dimeric copper complex of the unsubstituted pyridoxal thiosemicarbazone (H2L),[{Cu
(HL)(OH2)} 2] Cl2· 2H2O, previously tested on Friend murine cell lines has been recently …