Effectiveness of rosuvastatin plus colchicine, emtricitabine/tenofovir and combinations thereof in hospitalized patients with COVID-19: a pragmatic, open-label …

HG Gaitán-Duarte, C Álvarez-Moreno… - …, 2022 - thelancet.com
Background The use of rosuvastatin plus colchicine and emtricitabine/tenofovir in
hospitalized patients with SARS-CoV-2 disease (COVID-19) has not been assessed. The …

Colchicine and high-intensity rosuvastatin in the treatment of non-critically ill patients hospitalised with COVID-19: a randomised clinical trial

T Shah, M McCarthy, I Nasir, H Archer, E Ragheb… - BMJ open, 2023 - bmjopen.bmj.com
Objective To evaluate the effect of colchicine and high-intensity rosuvastatin in addition to
standard of care on the progression of COVID-19 disease in hospitalised patients. Design A …

[HTML][HTML] Atorvastatin therapy in COVID-19 adult inpatients: A double-blind, randomized controlled trial

L Davoodi, H Jafarpour, Z Oladi, Z Zakariaei… - IJC Heart & …, 2021 - Elsevier
Introduction Efficacious therapies are urgently required to tackle the coronavirus disease
2019 (COVID-19). This trial aims to evaluate the effects of atorvastatin in comparison with …

Promising effects of atorvastatin on mortality and need for mechanical ventilation in patients with severe COVID‐19; a retrospective cohort study

M Haji Aghajani, O Moradi… - … Journal of Clinical …, 2021 - Wiley Online Library
Purpose Considering the anti‐inflammatory effect of atorvastatin and the role of medical
comorbidities such as hypertension and coronary artery disease on the prognosis of the …

Statins in hospitalized COVID‐19 patients: A systematic review and meta‐analysis of randomized controlled trials

Y Ren, G Wang, D Han - Journal of Medical Virology, 2023 - Wiley Online Library
This systematic review and meta‐analysis aimed to determine the efficacy of statins in
hospitalized patients with coronavirus disease‐2019 (COVID‐19). A systematic search was …

Simvastatin in critically ill patients with Covid-19

REMAP-CAP Investigators - New England Journal of Medicine, 2023 - Mass Medical Soc
Background The efficacy of simvastatin in critically ill patients with coronavirus disease 2019
(Covid-19) is unclear. Methods In an ongoing international, multifactorial, adaptive platform …

Atorvastatin efficacy in the management of mild to moderate hospitalized COVID-19: A pilot randomized triple-blind placebo-controlled clinical trial

S Hejazi, F Mircheraghi, S Elyasi… - Recent Advances in …, 2022 - ingentaconnect.com
Background: Statins are first-line lipid-lowering agents with tolerable adverse reactions, low
cost, and high availability worldwide. The potent anti-inflammatory, antioxidant, anti …

Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial

N Ghati, A Roy, S Bhatnagar, S Bhati, S Bhushan… - Trials, 2020 - Springer
Objectives To assess the impact of adding statin (atorvastatin) and/or aspirin on clinical
deterioration in patients infected with SARS-CoV-2 who require hospitalisation. The safety of …

Statin and aspirin as adjuvant therapy in hospitalised patients with SARS-CoV-2 infection: a randomised clinical trial (RESIST trial)

N Ghati, S Bhatnagar, M Mahendran, A Thakur… - BMC infectious …, 2022 - Springer
Background Statins and aspirin have been proposed for treatment of COVID-19 because of
their anti-inflammatory and anti-thrombotic properties. Several observational studies have …

Systematic review and meta-analysis of statin use and mortality, intensive care unit admission and requirement for mechanical ventilation in COVID-19 patients

US Lao, CF Law, DT Baptista-Hon… - Journal of Clinical …, 2022 - mdpi.com
There is mounting evidence that statin use is beneficial for COVID-19 outcomes. We
performed a systematic review and meta-analysis to evaluate the association between statin …