Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

M Mattheisen, J Grove, TD Als, J Martin, G Voloudakis… - Nature Genetics, 2022 - nature.com
Attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are
highly heritable neurodevelopmental conditions, with considerable overlap in their genetic …

Identification of common genetic risk variants for autism spectrum disorder

J Grove, S Ripke, TD Als, M Mattheisen, RK Walters… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search …

NNJ Rommelse, HM Geurts, B Franke… - Neuroscience & …, 2011 - Elsevier
We propose to bring together the hitherto rather separate research fields of autism spectrum
disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), and argue that by …

[HTML][HTML] Genetic architecture of autism spectrum disorder: Lessons from large-scale genomic studies

L Choi, JY An - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic
component. Recently developed genomic technologies, including microarray and next …

Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes

J Elia, X Gai, HM Xie, JC Perin, E Geiger… - Molecular …, 2010 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable disorder,
but specific genetic factors underlying risk remain elusive. To assess the role of structural …

[HTML][HTML] Patterns of psychiatric comorbidity and genetic correlations provide new insights into differences between attention-deficit/hyperactivity disorder and autism …

BS Solberg, T Zayats, MB Posserud, A Halmøy… - Biological …, 2019 - Elsevier
Background Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder
(ASD) share common genetic factors but seem to have specific patterns of psychiatric …

Rare coding variation provides insight into the genetic architecture and phenotypic context of autism

JM Fu, FK Satterstrom, M Peng, H Brand, RL Collins… - Nature …, 2022 - nature.com
Some individuals with autism spectrum disorder (ASD) carry functional mutations rarely
observed in the general population. We explored the genes disrupted by these variants from …

Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

VM Rajagopal, J Duan, L Vilar-Ribó, J Grove… - Nature …, 2022 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder with onset
in childhood (childhood ADHD); two-thirds of affected individuals continue to have ADHD in …

Genetic architecture in autism spectrum disorder

B Devlin, SW Scherer - Current opinion in genetics & development, 2012 - Elsevier
Autism spectrum disorder (ASD) is characterized by impairments in reciprocal social
interaction and communication, and by restricted and repetitive behaviors. Family studies …

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder

E Mick, A Todorov, S Smalley, X Hu, S Loo… - Journal of the American …, 2010 - Elsevier
OBJECTIVE: Genes likely play a substantial role in the etiology of attention-
deficit/hyperactivity disorder (ADHD). However, the genetic architecture of the disorder is …