Purpose To explore the molecular mechanism of luteolin in the treatment of osteoporosis
(OP) by network pharmacological prediction and experimentation. Methods The target …

In this study, the network pharmacology analysis method was used to explore the bioactive
components and targets of Xianlinggubao (XLGB) and further elucidate its potential …

Postmenopausal osteoporosis (PMOP) has became 1 of most prevalent bone disorders with
aging population. Liuwei Dihuang (LWDH) Pill, a classical kidney-tonifying prescription, is …

Background Luteolin is an active ingredient in various traditional Chinese medicines for the
treatment of multiple tumors. However, the mechanisms of its inhibitory effect on …

Abstract Background Liuwei Dihuang Pill (LP) was verified to alleviate postmenopausal
osteoporosis (PMOP) development. Nevertheless, the major constituent of LP and the …

Glucocorticoid‐induced osteoporosis (GIO) is a secondary osteoporosis with extensive use
of glucocorticoids (GCs). GCs can increase bone fragility and fracture via inhibiting …

Abstract Tenghuang Jiangu Capsule (THJGC) is a Chinese herbal formula used for the
treatment of osteoporosis and osteoarthritis in China, but its mechanism for treating …

Background. With the advent of ageing population, osteoporosis (OP) has already become a
global challenge. Jintiange capsule is extensively applied to treat OP in China. Although …

Osteoporosis (OP) is a systemic disease susceptible to fracture due to the decline of bone
mineral density and bone mass, the destruction of bone tissue microstructure, and increased …

Background: Although Semaphorin 3A (Sema3A)/Neuropilin-1 (NRP1)/Plexin A1 is one of
the important targets in bone metabolism, few studies are performed on this target in the …