The novel role of C-reactive protein in cardiovascular disease: risk marker or pathogen

AM Wilson, MC Ryan, AJ Boyle - International journal of cardiology, 2006 - Elsevier
C-reactive protein (CRP) is a non-specific biomarker of inflammation. Recent research has
shown that inflammation is an important step in the genesis of atherosclerosis, and is …

C-reactive protein in atherosclerosis: a causal factor?

E Paffen, MPM DeMaat - Cardiovascular research, 2006 - academic.oup.com
Atherosclerosis is considered a to be multifactorial disease driven by inflammatory reactions.
The process of inflammation also contributes to the pathogenesis of acute atherothrombotic …

The evolving role of C-reactive protein in atherothrombosis

S Devaraj, U Singh, I Jialal - Clinical chemistry, 2009 - academic.oup.com
Background: Inflammation is pivotal in all phases of atherosclerosis. Among the numerous
inflammatory biomarkers, the largest amount of published data supports a role for C-reactive …

C-reactive protein: interaction with the vascular endothelium and possible role in human atherosclerosis

C Ferri, G Croce, V Cofini… - Current …, 2007 - ingentaconnect.com
C-reactive protein (CRP) is the first acute phase protein that has been described in the
literature. It is phylogenetically ancient and-with serum amyloid P-belongs to proteins named …

C-reactive protein: risk marker or mediator in atherothrombosis?

I Jialal, S Devaraj, SK Venugopal - Hypertension, 2004 - Am Heart Assoc
Inflammation appears to be pivotal in all phases of atherosclerosis from the fatty streak
lesion to acute coronary syndromes. An important downstream marker of inflammation is C …

C-reactive protein and atherothrombosis: cause or effect?

E Grad, HD Danenberg - Blood reviews, 2013 - Elsevier
The complex relationship between the inflammatory response and vascular injury and repair
is of major importance to the pathogenesis of cardiovascular disease. CRP is not only a …

C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases

JJ Li, CH Fang - Medical hypotheses, 2004 - Elsevier
Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis and
mediate many of the stages of atheroma development from initial leukocyte recruitment to …

The role of C-reactive protein in atherosclerotic cardiovascular disease: an overview

ES Nakou, EN Liberopoulos… - Current Vascular …, 2008 - ingentaconnect.com
C-reactive protein (CRP) is an acute-phase protein, which has been used in clinical practice
as a non specific marker of inflammation. Many studies have shown that CRP is associated …

C-reactive protein, inflammation, and coronary risk

DA Morrow, PM Ridker - Medical Clinics of North America, 2000 - Elsevier
Despite progress in the prevention of cardiovascular disease, a significant proportion of first
cardiovascular events occurs among individuals without traditional risk factors. Given the …

CRP and the risk of atherosclerotic events

P Calabrò, E Golia, ETH Yeh - Seminars in immunopathology, 2009 - Springer
A large body of literature supports the idea that inflammation plays a pivotal role in all
phases of atherosclerosis, from the fatty streak lesion formation to the acute coronary event …