[HTML][HTML] Identification of hub genes associated with Helicobacter pylori infection and type 2 diabetes mellitus: A pilot bioinformatics study

H Chen, GX Zhang, XY Zhou - World Journal of Diabetes, 2024 - ncbi.nlm.nih.gov
Identification of hub genes associated with Helicobacter pylori infection and type 2 diabetes
mellitus: A pilot bioinformatics study - PMC Back to Top Skip to main content NIH NLM Logo …

Identification of shared hub genes and pathways between gastric cancer and Helicobacter pylori infection through bioinformatics analysis

R Maddah, Z Molavi, HM Ehymayed, F Miri, P Shariati… - Human Gene, 2024 - Elsevier
Background Gastric cancer (GC), the third leading cause of cancer-related deaths, has
become a worldwide health issue. Gastric cancer is causally associated with Helicobacter …

Identification of hub genes and signaling pathways related to gastric cells infected by Helicobacter pylori

SY Gu, XJ Cao, Y Feng, QQ Wei, JQ Liang, LM Xie… - Microbial …, 2021 - Elsevier
Background Helicobacter pylori is a pathogen involved in several gastroduodenal diseases,
whose infection mechanisms have not been completely confirmed. To study the specific …

Association between Helicobacter pylori infection and type 2 diabetes mellitus: a retrospective cohort study and bioinformatics analysis

J Li, W Yuan, J Liu, B Yang, X Xu, X Ren, L Jia - BMC Endocrine Disorders, 2024 - Springer
Purpose This study aimed to preliminarily investigate the association and possible
mechanisms between Helicobacter. pylori (H. pylori) infection and type 2 diabetes mellitus …

[HTML][HTML] Unveiling HuB genes and drug design against Helicobacter pylori infection by network biology and biophysics techniques

S Javed, S Ahmad, A Naz, A Ullah, SM Aljahdali… - Informatics in Medicine …, 2024 - Elsevier
Helicobacter pylori (H. pylori) is mainly considered for causing chronic gastritis, which can
lead to several secondary complications like peptic ulcer and pre-malignant lesions for …

Causal relationships of Helicobacter pylori and related gastrointestinal diseases on Type 2 diabetes: Univariable and Multivariable Mendelian randomization

M Sun, Z Zhang, J Zhang, J Zhang, Z Jia, L Zhao… - Plos one, 2024 - journals.plos.org
Background Previous observational studies have demonstrated a connection between the
risk of Type 2 diabetes mellitus (T2DM) and gastrointestinal problems brought on by …

Bioinformatic identification of key pathways, hub genes, and microbiota for therapeutic intervention in Helicobacter pylori infection

Z Chen, H Chen, L Yu, H Xin, J Kong… - Journal of Cellular …, 2021 - Wiley Online Library
The pathogenic mechanisms of Helicobacter pylori infection remain to be defined, and
potential interventional microbiota are just beginning to be identified. In this study, gene‐set …

[HTML][HTML] Hub gene identification and molecular subtype construction for Helicobacter pylori in gastric cancer via machine learning methods and NMF algorithm

L Luo, A Wu, X Shu, L Liu, Z Feng, Q Zeng… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Helicobacter pylori (HP) is a gram-negative and spiral-shaped bacterium colonizing the
human stomach and has been recognized as the risk factor of gastritis, peptic ulcer disease …

[HTML][HTML] Identification of core genes associated with type 2 diabetes mellitus and gastric cancer by bioinformatics analysis

S Liu, Y Zhao, R Duan, Y Wu, X Chen… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background Gastric cancer (GC) is the most common type of malignant neoplasm of the
digestive system. Diabetes mellitus (DM) or hyperglycemia may increase the incidence or …

[HTML][HTML] Identifying key genes and screening therapeutic agents associated with diabetes mellitus and HCV-related hepatocellular carcinoma by bioinformatics …

M Sufyan, UA Ashfaq, S Ahmad, F Noor… - Saudi Journal of …, 2021 - Elsevier
Abstract Objective Incidence of both Type 2 diabetes mellitus (T2DM) and hepatocellular
carcinoma (HCC) are rapidly increasing worldwide. One of the leading causes of HCC is …