Background Despite previous randomised trials of early β-blocker therapy in the emergency
treatment of myocardial infarction (MI), uncertainty has persisted about the value of adding it …

Objectives: The goal of this trial was to study the long-term effects of intravenous (IV)
metoprolol administration before reperfusion on left ventricular (LV) function and clinical …

In the Göteborg Metoprolol Trial, 1395 patients with suspected acute myocardial infarction
were, on admission, randomly allocated to double-blind treatment, 697 to placebo and 698 …

The effect of metoprolol on mortality and morbidity after 15 days, was compared with that of
placebo in a double-blind randomised international trial (the MIAMI trial) in patients with …

The effects of metoprolol treatment in patients surviving acute myocardial infarction have
been investigated in a double-blind randomized study. The patients were stratified …

Background—The effect of β-blockers on infarct size when used in conjunction with primary
percutaneous coronary intervention is unknown. We hypothesize that metoprolol reduces …

The aim of this study is to describe the impact of early treatment with metoprolol on
prognosis during 1 year of follow-up in patients with suspected acute myocardial infarction …

Several postinfarction trials have evaluated the effect of secondary prophylaxis with different
beta-blockers. Although so called meta-analysis of the results from all the trials have shown …

Background: The impact of intravenous (IV) beta-blockers before primary percutaneous
coronary intervention (PPCI) on infarct size and clinical outcomes is not well established …

Background: Beta-blocker therapy after acute myocardial infarction (MI) improves survival.
Beta-blocker doses used in clinical practice are often substantially lower than those used in …