Antibiotics released locally through a carrier is a commonly used technique to prevent
infection in orthopaedic procedures. Antibiotic-impregnated bone chips are an interesting …

Aim Local antibiotics released through a carrier is a commonly used technique to prevent
infection in orthopaedic procedures. An interesting carrier in aseptic bone reconstructive …

Background Antimicrobial prophylaxis is considered beneficial for preventing surgical-site
infections in clean orthopaedic surgery. However, whether tissue concentrations of cefazolin …

Background Allograft bone used in joint replacement surgery can additionally serve as a
carrier for antibiotics and serve as a prophylaxis against infections. However, in vitro dose …

Bone grafts are used for reconstructing bone defects caused by implant-associated
complications, trauma, and tumors. Surgery with bone allografts is complex and time …

Substitution of bones is a well-established, necessary procedure to treat bone defects in
trauma and orthopedic surgeries. For prevention or treatment of perioperative infection, the …

We investigated the antibiotic concentration in fresh-frozen femoral head allografts
harvested from two groups of living donors. Ten samples were collected from patients with …

We investigated in an animal model the efficacy of tobramycin‐containing bone cement and
systemic cefazolin for infection prophylaxis. In 18 female rabbits, the femoral cavity was …

Abstract Backgrounds and Objectives The use of local antibiotic delivery vehicles is common
in the management of biofilm-related infections as they provide high concentrations of local …

Osteomyelitis remains a significant complication in orthopedic surgeries. Although infection
rates remain steady at 1-3% for primary orthopedic surgeries, overall numbers of orthopedic …