Introduction Bipolar disorder (BD) is a severe and recurrent psychiatric disorder. The
severity of prognosis in BD is mainly linked to the high rate of suicide in this population …

The management and treatment of patients with suicidal behavior is one of the most
challenging tasks for health-care professionals. Patients with affective disorders are at high …

Objective To assess whether lithium has a specific preventive effect for suicide and self harm
in people with unipolar and bipolar mood disorders. Design Systematic review and meta …

Background Excess mortality is a critical hallmark of bipolar disorder (BD) due to co‐
occurring general medical disorders and especially from suicide. It is timely to review of the …

The article reviews the existing evidence and the concept of the anti-suicidal effect of lithium
long-term treatment in bipolar patients. The core studies supporting the concept of a suicide …

Objectives Suicide and suicidal behaviour are increased in mood disorders, particularly
bipolar disorders. Observational studies and small randomized controlled trials (RCTs) …

Background Mortality rates, in particular due to suicide, are especially high in bipolar
patients. This nationwide, registry-based study analyses the associations of medication use …

Background In a previous meta-analysis of randomized controlled trials comparing lithium
with placebo as a long-term treatment in bipolar disorders, we observed a clear preventative …

Unipolar depression is a severe recurrent illness with high lifetime morbidity and premature
mortality due to suicide. Numerous double-blind, placebo-controlled trials have shown that …

Objective: To review studies of (A) whether lithium has a prophylactic action in bipolar
disorder,(B) the efficacy of prophylactic lithium treatment in comparison with the efficacy of …