[HTML][HTML] C-type lectins in immunity: recent developments

IM Dambuza, GD Brown - Current opinion in immunology, 2015 - Elsevier
Highlights•CLRs play an essential role in immunity to fungi and mycobacteria.•CLRs are
involved in the regulation of homeostasis, autoimmunity and allergy.•CLRs recognise and …

The Dectin-2 family of C-type lectin-like receptors: an update

B Kerscher, JA Willment, GD Brown - International immunology, 2013 - academic.oup.com
Myeloid and non-myeloid cells express members of the C-type lectin-like receptor (CTLR)
family, which mediate crucial cellular functions during immunity and homeostasis. Of …

Signalling C‐type lectin receptors, microbial recognition and immunity

JC Hoving, GJ Wilson, GD Brown - Cellular microbiology, 2014 - Wiley Online Library
Signalling C‐type lectin receptors (CLR s) are crucial in shaping the immune response to
fungal pathogens, but comparably little is known about the role of these receptors in …

Signalling C-type lectins in antimicrobial immunity

RA Drummond, GD Brown - PLoS pathogens, 2013 - journals.plos.org
Since it was first proposed that the innate immune system could recognise conserved
microbial-associated molecular patterns (or PAMPs) through inherited receptors expressed …

C-type lectins on dendritic cells: key modulators for the induction of immune responses

Y Van Kooyk - Biochemical Society Transactions, 2008 - portlandpress.com
DCs (dendritic cells) are specialized in the recognition of pathogens and play a pivotal role
in the control of immune responses. DCs are also important for homoeostatic control …

C-type lectins: their network and roles in pathogen recognition and immunity

S Mayer, MK Raulf, B Lepenies - Histochemistry and cell biology, 2017 - Springer
C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …

C-type lectin-like receptors as emerging orchestrators of sterile inflammation represent potential therapeutic targets

E Chiffoleau - Frontiers in immunology, 2018 - frontiersin.org
Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid
cells, have gained increasing attention for their role in the fine tuning of both innate and …

Immune escape through C-type lectins on dendritic cells

A Engering, TBH Geijtenbeek, Y van Kooyk - Trends in immunology, 2002 - cell.com
Dendritic cells (DCs) detect different pathogens and elicit tailored anti-microbial immune
responses. They express C-type lectins that recognise carbohydrate profiles on …

C-type lectin receptors in antifungal immunity

JA Willment, GD Brown - Trends in microbiology, 2008 - cell.com
Fungal infections represent a significant health burden, especially in immunocompromised
individuals, yet many of the underlying immunological mechanisms involved in the …

[HTML][HTML] The Dectin-2 family of C-type lectins in immunity and homeostasis

LM Graham, GD Brown - Cytokine, 2009 - Elsevier
C-type lectins are a diverse family of proteins which recognize a wide range of ligands. This
review focuses on the Dectin-2 family of C-type lectins that includes Dectin-2, BDCA-2 …