[HTML][HTML] Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases

RM Meganck, RS Baric - Nature medicine, 2021 - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …

[HTML][HTML] A painful lesson from the COVID-19 pandemic: the need for broad-spectrum, host-directed antivirals

VC Chitalia, AH Munawar - Journal of translational medicine, 2020 - Springer
While the COVID-19 pandemic has spurred intense research and collaborative discovery
worldwide, the development of a safe, effective, and targeted antiviral from the ground up is …

COVID-19 therapeutics: Challenges and directions for the future

PC Robinson, DFL Liew, HL Tanner… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of SARS-CoV-2 triggering the COVID-19 pandemic ranks as arguably the
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …

[HTML][HTML] Antiviral drug discovery: preparing for the next pandemic

CS Adamson, K Chibale, RJM Goss… - Chemical Society …, 2021 - pubs.rsc.org
Clinically approved antiviral drugs are currently available for only 10 of the more than 220
viruses known to infect humans. The SARS-CoV-2 outbreak has exposed the critical need …

Research and development on therapeutic agents and vaccines for COVID-19 and related human coronavirus diseases

C Liu, Q Zhou, Y Li, LV Garner, SP Watkins, LJ Carter… - 2020 - ACS Publications
Since the outbreak of the novel coronavirus disease COVID-19, caused by the SARS-CoV-2
virus, this disease has spread rapidly around the globe. Considering the potential threat of a …

Drug combinations as a first line of defense against coronaviruses and other emerging viruses

JM White, JT Schiffer, RA Bender Ignacio, S Xu… - MBio, 2021 - Am Soc Microbiol
The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-
equipped for future pandemics. While unprecedented strides have been made developing …

[引用][C] Long-COVID treatments: why the world is still waiting

H Ledford - Nature, 2022 - ideas.repec.org
Long-COVID treatments: why the world is still waiting IDEAS home Advanced search Economic
literature: papers, articles, software, chapters, books. Authors Institutions Rankings Help/FAQ …

Emerging viral diseases: confronting threats with new technologies

HD Marston, GK Folkers, DM Morens… - Science translational …, 2014 - science.org
Emerging Viral Diseases: Confronting Threats with New Technologies | Science Translational
Medicine news careers commentary Journals Science Science brought to you byGoogle Indexer …

The pandemic pipeline

J Hodgson - Nat Biotechnol, 2020 - nature.com
This week, Moderna Therapeutics' modified mRNA vaccine for COVID-19 began phase 1
clinical testing. From the first description of the novel coronavirus (SARS-CoV-2) genome on …

Creating a framework for conducting randomized clinical trials during disease outbreaks

NE Dean, PS Gsell, R Brookmeyer… - … England Journal of …, 2020 - Mass Medical Soc
Responding to Global Infectious Disease Outbreaks As in the ongoing Covid-19 pandemic,
global outbreaks of infectious illnesses often develop quickly and resolve in unpredictable …