Stimulation of bone repair with ultrasound: a review of the possible mechanic effects

F Padilla, R Puts, L Vico, K Raum - Ultrasonics, 2014 - Elsevier
In vivo and in vitro studies have demonstrated the positive role that ultrasound can play in
the enhancement of fracture healing or in the reactivation of a failed healing process. We …

[HTML][HTML] The enhancement of bone regeneration by ultrasound

L Claes, B Willie - Progress in biophysics and molecular biology, 2007 - Elsevier
Millions of fractures occur every year worldwide, with nearly 6.2 million fractures reported
annually in the United States alone. Even though treatment methods have improved over the …

[HTML][HTML] Mode & mechanism of low intensity pulsed ultrasound (LIPUS) in fracture repair

A Harrison, S Lin, N Pounder, Y Mikuni-Takagaki - Ultrasonics, 2016 - Elsevier
It has been 30 years since the first level one clinical trial demonstrated low intensity pulsed
ultrasound (LIPUS) could accelerate fracture repair. Since 1994 numerous investigations …

[HTML][HTML] Ultrasound as a stimulus for musculoskeletal disorders

N Zhang, SKH Chow, KS Leung, WH Cheung - Journal of orthopaedic …, 2017 - Elsevier
Ultrasound is an inaudible form of acoustic sound wave at 20 kHz or above that is widely
used in the medical field with applications including medical imaging and therapeutic …

Low intensity pulsed ultrasound for fracture healing: a review of the clinical evidence and the associated biological mechanism of action

NM Pounder, AJ Harrison - Ultrasonics, 2008 - Elsevier
Low intensity pulsed ultrasound is used in the clinical treatment of fractures and other
osseous defects. Level I clinical studies demonstrate the ability of a specific ultrasound …

Enhancement of fracture healing by low intensity ultrasound.

M Hadjiargyrou, K McLeod, JP Ryaby… - … and Related Research …, 1998 - journals.lww.com
Fracture healing is a highly complex regenerative process that is essentially a replay of
developmental events. These events include the action of many different cell types, a myriad …

Fracture repair with ultrasound: clinical and cell-based evaluation

Y Khan, CT Laurencin - JBJS, 2008 - journals.lww.com
Fracture repair continues to be widely investigated, both within the clinical realm and at the
fundamental research level, in part due to the fact that 5% to 10% of fractures result in either …

Low‐intensity pulsed ultrasound stimulation for bone fractures healing: a review

P Palanisamy, M Alam, S Li… - Journal of Ultrasound …, 2022 - Wiley Online Library
Low‐intensity pulsed ultrasound (LIPUS) is a developing technology, which has been
proven to improve fracture healing process with minimal thermal effects. This noninvasive …

Regulation by ultrasound treatment on the integrin expression and differentiation of osteoblasts

RS Yang, WL Lin, YZ Chen, CH Tang, TH Huang… - Bone, 2005 - Elsevier
It has been shown that ultrasound (US) stimulation accelerates fracture healing in the animal
models and in clinical studies. However, the mechanism by which US achieves these …

The use of low-intensity ultrasound to accelerate the healing of fractures

C Rubin, M Bolander, JP Ryaby, M Hadjiargyrou - JBJS, 2001 - journals.lww.com
® The effectiveness of low-intensity ultrasound has also been demonstrated in the clinical
treatment of delayed unions and nonunions. racture-healing is a complex biological process …