The role of N6-methyladenosine (m6A) in kidney diseases

L You, Z Han, H Chen, L Chen, Y Lin, B Wang… - Frontiers in …, 2023 - frontiersin.org
Chemical modifications are a specific and efficient way to regulate the function of biological
macromolecules. Among them, RNA molecules exhibit a variety of modifications that play …

The role of N-methyladenosine modification in acute and chronic kidney diseases

S Qi, J Song, L Chen, H Weng - Molecular Medicine, 2023 - Springer
Abstract N 6-methyladenosine (m6A) modification is a kind of RNA modification in which
methylation occurs at the sixth N position in adenosine in RNA, which can occur in various …

[HTML][HTML] N6-methyladenine RNA methylation epigenetic modification and kidney diseases

J Luan, JB Kopp, H Zhou - Kidney International Reports, 2023 - Elsevier
RNA methylation modification is a rapidly developing field in epigenetics. N6-
methyladensine (m 6 A) is the most common internal modification in eukaryotic mRNA. m 6 …

N6-methyladenosine methylation in kidney injury

Q Wang, X Fan, Q Sheng, M Yang, P Zhou, S Lu… - Clinical …, 2023 - Springer
Multiple mechanisms are involved in kidney damage, among which the role of epigenetic
modifications in the occurrence and development of kidney diseases is constantly being …

N6-methyladenosine (m6A) methylation in kidney diseases: Mechanisms and therapeutic potential

Y Sun, D Jin, Z Zhang, H Ji, X An, Y Zhang… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Abstract The N6-methyladenosine (m6A) modification is regulated by methylases, commonly
referred to as “writers,” and demethylases, known as “erasers,” leading to a dynamic and …

RNA N6‐methyladenosine modifications and potential targeted therapeutic strategies in kidney disease

WJ Ni, H Lu, NN Ma, BB Hou, J Zeng… - British Journal of …, 2023 - Wiley Online Library
Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …

Roles of N6‐methyladenosine (m6A) RNA modifications in urological cancers

X Wang, H Xie, Y Ying, D Chen… - Journal of Cellular and …, 2020 - Wiley Online Library
Epigenetics has long been a hot topic in the field of scientific research. The scope of
epigenetics usually includes chromatin remodelling, DNA methylation, histone …

RNA N6-methyladenosine modifications in urological cancers: from mechanism to application

L Yang, J Ying, Q Tao, Q Zhang - Nature Reviews Urology, 2024 - nature.com
Abstract The N6‐methyladenosine (m6A) modification is the most common modification of
messenger RNAs in eukaryotes and has crucial roles in multiple cancers, including in …

N6‐Methyladenosine (m6A) readers are dysregulated in renal cell carcinoma

F von Hagen, L Gundert, A Strick… - Molecular …, 2021 - Wiley Online Library
Abstract N6‐Methyladenosine (m6A) is the most common modification of messenger RNA
(mRNA) in mammals. It critically influences RNA metabolism and plays an essential role in …

The potential roles of RNA N6-methyladenosine in urological tumors

Y Li, Y Ge, L Xu, Z Xu, Q Dou, R Jia - Frontiers in Cell and …, 2020 - frontiersin.org
N6-methyladenosine (m6A) is regarded as the most abundant, prevalent and conserved
internal mRNA modification in mammalian cells. M6A can be catalyzed by m6A …