[HTML][HTML] Frontal white matter hyperintensities and executive functioning performance in older adults

EM Boutzoukas, A O'Shea, A Albizu… - Frontiers in aging …, 2021 - frontiersin.org
Frontal lobe structures decline faster than most other brain regions in older adults. Age-
related change in the frontal lobe is associated with poorer executive function (eg, working …

Lesion location matters: the relationships between white matter hyperintensities on cognition in the healthy elderly

L Lampe, S Kharabian-Masouleh… - Journal of Cerebral …, 2019 - journals.sagepub.com
White matter hyperintensities (WMH) are associated with cognitive decline. We aimed to
identify the spatial specificity of WMH impact on cognition in non-demented, healthy elderly …

White matter hyperintensities across the adult lifespan: relation to age, Aβ load, and cognition

A Garnier-Crussard, S Bougacha, M Wirth… - Alzheimer's research & …, 2020 - Springer
Background White matter hyperintensities (WMH) are very frequent in older adults and
associated with worse cognitive performance. Little is known about the links between WMH …

The association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent

HIL Jacobs, PJ Visser, MPJ Van Boxtel, GB Frisoni… - Neurobiology of …, 2012 - Elsevier
White matter hyperintensities (WMH) in Mild Cognitive Impairment (MCI) have been
associated with impaired executive functioning, although contradictory findings have been …

Patterns of white matter hyperintensities associated with cognition in middle-aged cognitively healthy individuals

A Brugulat-Serrat, G Salvadó, CH Sudre… - Brain imaging and …, 2020 - Springer
White matter hyperintensities (WMH) are commonly detected in the brain of elderly
individuals and have been associated with a negative impact on multiple cognitive domains …

[HTML][HTML] Executive functions in healthy older adults are differentially related to macro-and microstructural white matter characteristics of the cerebral lobes

S Hirsiger, V Koppelmans, S Mérillat, C Erdin… - Frontiers in Aging …, 2017 - frontiersin.org
Aging is associated with microstructural white matter (WM) changes. WM microstructural
characteristics, measured with diffusion tensor imaging (DTI), are different in normal …

Functional impact of white matter hyperintensities in cognitively normal elderly subjects

ME Murray, ML Senjem, RC Petersen… - Archives of …, 2010 - jamanetwork.com
Objective To investigate the impact white matter hyperintensities (WMH) detected on
magnetic resonance imaging have on motor dysfunction and cognitive impairment in elderly …

White matter hyperintensities are associated with impairment of memory, attention, and global cognitive performance in older stroke patients

EJ Burton, RA Kenny, J O'Brien, S Stephens… - Stroke, 2004 - Am Heart Assoc
Background—The importance of white matter hyperintensities (WMH) for cognitive
performance in older stroke patients is largely unknown. We hypothesized that processing …

White matter abnormalities and cognition in a community sample

TD Vannorsdall, SR Waldstein, M Kraut… - Archives of clinical …, 2009 - academic.oup.com
White matter hyperintensities (WMH) can compromise cognition in older adults, but
differences in sampling, WMH measurements, and cognitive assessments contribute to …

White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age

PA Boyle, L Yu, DA Fleischman… - Annals of clinical …, 2016 - Wiley Online Library
Objective Examine the association of white matter hyperintensities (WMH) with risk of
incident mild cognitive impairment (MCI) and rate of decline in multiple cognitive systems in …