Thirty years after the discovery of HIV-1, the early transmission, dissemination, and
establishment of the virus in human populations remain unclear. Using statistical …

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In this study we date the introduction of HIV-2 into the human population and estimate the
epidemic history of HIV-2 subtype A in Guinea-Bissau, the putative geographic origin of HIV …

Design: We sought to investigate the evolutionary and historical reasons for the different
epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the …

The global response to the HIV/AIDS epidemic, which has already infected more than 50
million people, has been inadequate, particularly in the developing world. In many countries …

The spread of HIV-1 in Africa is examined here in the light of recent information on the main
epidemiological and behavioural determinants of transmission. Mathematical models …

Sociocultural factors during the postcolonial period have been implicated as paramount in
generating conditions that promoted both the origin and subsequent epidemic spread of HIV …

By the end of 1987, nearly 50,000 cases of acquired immunodeficiency syndrome (AIDS)
had been reported since 1981, 20,745 in the past year alone. Black and Hispanic adults and …

The emergence of HIV-1 group M subtype B in North American men who have sex with men
was a key turning point in the HIV/AIDS pandemic. Phylogenetic studies have suggested …

Significant differences have been observed in the rates of transmission and disease
development in human immunodeficiency virus (HIV) types 1 and 2. Because many HIV-2 …