Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens
Deployment of nucleic acid amplification assays for diagnosing pathogens in point-of-care
settings is a challenge due to lengthy preparatory steps. We present a molecular diagnostic …
settings is a challenge due to lengthy preparatory steps. We present a molecular diagnostic …
Multiplexed reverse-transcriptase quantitative polymerase chain reaction using plasmonic nanoparticles for point-of-care COVID-19 diagnosis
NR Blumenfeld, MAE Bolene, M Jaspan… - Nature …, 2022 - nature.com
Quantitative polymerase chain reaction (qPCR) offers the capabilities of real-time monitoring
of amplified products, fast detection, and quantitation of infectious units, but poses technical …
of amplified products, fast detection, and quantitation of infectious units, but poses technical …
Ultrafast and real-time nanoplasmonic on-chip polymerase chain reaction for rapid and quantitative molecular diagnostics
Advent and fast spread of pandemic diseases draw worldwide attention to rapid, prompt,
and accurate molecular diagnostics with technical development of ultrafast polymerase …
and accurate molecular diagnostics with technical development of ultrafast polymerase …
Multiplexed and high-throughput label-free detection of RNA/spike protein/IgG/IgM biomarkers of SARS-CoV-2 infection utilizing nanoplasmonic biosensors
AN Masterson, BB Muhoberac, A Gopinadhan… - Analytical …, 2021 - ACS Publications
To tackle the COVID-19 outbreak, which is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), there is an unmet need for highly accurate diagnostic tests at …
coronavirus 2 (SARS-CoV-2), there is an unmet need for highly accurate diagnostic tests at …
Ultrafast plasmonic nucleic acid amplification and real-time quantification for decentralized molecular diagnostics
Point-of-care real-time reverse-transcription polymerase chain reaction (RT-PCR) facilitates
the widespread use of rapid, accurate, and cost-effective near-patient testing that is …
the widespread use of rapid, accurate, and cost-effective near-patient testing that is …
RNA-extraction-free nano-amplified colorimetric test for point-of-care clinical diagnosis of COVID-19
The global pandemic of coronavirus disease 2019 (COVID-19) highlights the shortcomings
of the current testing paradigm for viral disease diagnostics. Here, we report a stepwise …
of the current testing paradigm for viral disease diagnostics. Here, we report a stepwise …
PD-LAMP smartphone detection of SARS-CoV-2 on chip
Abstract In 2019 the COVID-19 pandemic, caused by SARS-CoV-2, demonstrated the urgent
need for rapid, reliable, and portable diagnostics. The COVID-19 pandemic was declared in …
need for rapid, reliable, and portable diagnostics. The COVID-19 pandemic was declared in …
A point-of-care microfluidic biosensing system for rapid and ultrasensitive nucleic acid detection from clinical samples
Rapid and ultrasensitive point-of-care RNA detection plays a critical role in the diagnosis
and management of various infectious diseases. The gold-standard detection method of …
and management of various infectious diseases. The gold-standard detection method of …
Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out
With its origin estimated around December 2019 in Wuhan, China, the ongoing SARS-CoV-
2 pandemic is a major global health challenge. The demand for scalable, rapid and …
2 pandemic is a major global health challenge. The demand for scalable, rapid and …
Accessible detection of SARS-CoV-2 through molecular nanostructures and automated microfluidics
Accurate and accessible nucleic acid diagnostics is critical to reducing the spread of COVID-
19 and resuming socioeconomic activities. Here, we present an integrated platform for the …
19 and resuming socioeconomic activities. Here, we present an integrated platform for the …