Persistent systemic microbial translocation and intestinal damage during coronavirus disease-19
A Oliva, MC Miele, F Di Timoteo, M De Angelis… - Frontiers in …, 2021 - frontiersin.org
Microbial translocation (MT) and intestinal damage (ID) are poorly explored in COVID-19.
Aims were to assess whether alteration of gut permeability and cell integrity characterize …
Aims were to assess whether alteration of gut permeability and cell integrity characterize …
Intestinal permeability changes with bacterial translocation as key events modulating systemic host immune response to SARS-CoV-2: A working hypothesis
V Cardinale, G Capurso, G Ianiro, A Gasbarrini… - Digestive and Liver …, 2020 - Elsevier
The microbiota-gut-liver-lung axis plays a bidirectional role in the pathophysiology of a
number of infectious diseases. During the course of severe acute respiratory syndrome …
number of infectious diseases. During the course of severe acute respiratory syndrome …
Plasma markers of disrupted gut permeability in severe COVID-19 patients
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …
severity during respiratory-related diseases. Lung injury causes systemic inflammation …
Severe COVID-19 is fueled by disrupted gut barrier integrity
ABSTRACT A disruption of the crosstalk between the gut and the lung has been implicated
as a driver of severity during respiratory-related diseases. Lung injury causes systemic …
as a driver of severity during respiratory-related diseases. Lung injury causes systemic …
[HTML][HTML] Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation
The microbial populations in the gut microbiome have recently been associated with COVID-
19 disease severity. However, a causal impact of the gut microbiome on COVID-19 patient …
19 disease severity. However, a causal impact of the gut microbiome on COVID-19 patient …
Plasma microbiome in COVID-19 subjects: An indicator of gut barrier defects and dysbiosis
R Prasad, MJ Patton, JL Floyd, S Fortmann… - International Journal of …, 2022 - mdpi.com
The gut is a well-established route of infection and target for viral damage by SARS-CoV-2.
This is supported by the clinical observation that about half of COVID-19 patients exhibit …
This is supported by the clinical observation that about half of COVID-19 patients exhibit …
Gut microbiome alterations and gut barrier dysfunction are associated with host immune homeostasis in COVID-19 patients
Z Sun, ZG Song, C Liu, S Tan, S Lin, J Zhu, FH Dai… - BMC medicine, 2022 - Springer
Background COVID-19 is an infectious disease characterized by multiple respiratory and
extrapulmonary manifestations, including gastrointestinal symptoms. Although recent …
extrapulmonary manifestations, including gastrointestinal symptoms. Although recent …
[HTML][HTML] Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients
Mucosal barrier alterations may play a role in the pathogenesis of several diseases,
including COVID-19. In this study we evaluate the association between bacterial …
including COVID-19. In this study we evaluate the association between bacterial …
[HTML][HTML] Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling
Long COVID, a type of post-acute sequelae of SARS-CoV-2 (PASC), has been associated
with sustained elevated levels of immune activation and inflammation. However, the …
with sustained elevated levels of immune activation and inflammation. However, the …
Increase in gut permeability and oxidized ldl is associated with post-acute sequelae of SARS-CoV-2
Background Post-acute sequelae of SARS-CoV-2 (PASC) is marked by persistent or newly
developing symptoms beyond 4 weeks of infection. Investigating gut integrity, oxidized lipids …
developing symptoms beyond 4 weeks of infection. Investigating gut integrity, oxidized lipids …