MDR (multidrug resistance) refers to the phenomenon that after tumor cells develop
resistance to a chemotherapeutic drug, they also develop cross-resistance to other …

Extracellular vesicles (EVs), named as exosomes, were recently found to play important
roles in cell-cell communication by transducing various biochemical and genetic information …

The drugresistance caused by the long-term application of chemotherapeutic drugs is still
the obstacle and problem of current tumor treatment. Therefore, elucidating the mechanism …

As a common malignant tumor worldwide, the prognosis of hepatocellular carcinoma (HCC)
remains unsatisfactory, even though treatment methods have improved. Despite the …

Aim: The study aims to investigate the circumvention of multidrug resistance (MDR) in
colorectal cancer by modulating exosome-mediated transfer of MDR transporter regulatory …

Hepatocellular carcinoma (HCC) is a frequently seen malignant tumor globally. The
occurrence of cisplatin (DDP) resistance is one of the main reasons for the high mortality of …

Exosomes are small membrane vesicles with a diameter of 40–100 nm, which are released
into the intracellular environment. Exosomes could influence the genetic and epigenetic …

Drug resistance is a major impediment in cancer therapy which strongly reduces the
efficiency of anti-cancer drugs. Exosomes are extracellular vesicles with cup or spherical …

Highlights•MDR is a significant impediment to effective chemotherapeutic intervention
against cancer cells.•Exosomes are known to play a critical role in tumor progression …

Cancer is a major public health problem, and> 18.1 million new cancer cases are diagnosed
annually. Cancer can be treated with the help of several methods, such as surgery …