[HTML][HTML] Marine anticancer agents: An overview with a particular focus on their chemical classes

M Barreca, V Spanò, A Montalbano, M Cueto… - Marine drugs, 2020 - mdpi.com
The marine environment is a rich source of biologically active molecules for the treatment of
human diseases, especially cancer. The adaptation to unique environmental conditions led …

[HTML][HTML] Marine compounds and cancer: The first two decades of XXI century

SA Dyshlovoy, F Honecker - Marine Drugs, 2019 - mdpi.com
In 2019, the scientific and medical community celebrated the 50th anniversary of the
introduction of the very first marine-derived drug, Cytarabine, into clinics. Cytarabine (aka …

Marine pharmacology in 2005–2006: Antitumour and cytotoxic compounds

AMS Mayer, KR Gustafson - European Journal of Cancer, 2008 - Elsevier
During 2005 and 2006, marine pharmacology research directed towards the discovery and
development of novel antitumour agents was reported in 171 peer-reviewed articles. The …

[HTML][HTML] From seabed to bedside: A review on promising marine anticancer compounds

E Wang, MA Sorolla, PD Gopal Krishnan, A Sorolla - Biomolecules, 2020 - mdpi.com
The marine environment represents an outstanding source of antitumoral compounds and,
at the same time, remains highly unexplored. Organisms living in the sea synthesize a wide …

[HTML][HTML] Marine compounds and cancer: Updates 2020

SA Dyshlovoy, F Honecker - Marine Drugs, 2020 - mdpi.com
By the end of the year 2020, there are nine marine-derived anticancer drugs available on
the market, and the field is currently growing exponentially. This process is stipulated by …

[HTML][HTML] An updated review on marine anticancer compounds: The use of virtual screening for the discovery of small-molecule cancer drugs

V Ruiz-Torres, JA Encinar, M Herranz-Lopez… - Molecules, 2017 - mdpi.com
Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …

[HTML][HTML] Marine natural products: A source of novel anticancer drugs

SAM Khalifa, N Elias, MA Farag, L Chen, A Saeed… - Marine drugs, 2019 - mdpi.com
Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new
drugs with novel modes of action and thus considerable research has been conducted for …

Marine pharmacology in 2003–2004: anti-tumour and cytotoxic compounds

AMS Mayer, KR Gustafson - European Journal of Cancer, 2006 - Elsevier
During 2003 and 2004, marine pharmacology research directed towards the discovery and
development of novel anti-tumour agents was published in 163 peer-reviewed articles. The …

A clinical armamentarium of marine-derived anti-cancer compounds

JM Jimeno - Anti-Cancer Drugs, 2002 - journals.lww.com
The sea, covering 70% of the Earth's surface, offers a considerably broader spectrum of
biological diversity than terra firma. Containing approximately 75% of all living organisms …

[HTML][HTML] Exploring the diversity of the marine environment for new anti-cancer compounds

DL Dayanidhi, BC Thomas, JS Osterberg… - Frontiers in Marine …, 2021 - frontiersin.org
Marine ecosystems contain over 80% of the world's biodiversity, and many of these
organisms have evolved unique adaptations enabling survival in diverse and challenging …