SA Dyshlovoy, F Honecker - Marine Drugs, 2019 - mdpi.com
In 2019, the scientific and medical community celebrated the 50th anniversary of the introduction of the very first marine-derived drug, Cytarabine, into clinics. Cytarabine (aka …
AMS Mayer, KR Gustafson - European Journal of Cancer, 2008 - Elsevier
During 2005 and 2006, marine pharmacology research directed towards the discovery and development of novel antitumour agents was reported in 171 peer-reviewed articles. The …
E Wang, MA Sorolla, PD Gopal Krishnan, A Sorolla - Biomolecules, 2020 - mdpi.com
The marine environment represents an outstanding source of antitumoral compounds and, at the same time, remains highly unexplored. Organisms living in the sea synthesize a wide …
SA Dyshlovoy, F Honecker - Marine Drugs, 2020 - mdpi.com
By the end of the year 2020, there are nine marine-derived anticancer drugs available on the market, and the field is currently growing exponentially. This process is stipulated by …
Marine secondary metabolites are a promising source of unexploited drugs that have a wide structural diversity and have shown a variety of biological activities. These compounds are …
Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new drugs with novel modes of action and thus considerable research has been conducted for …
AMS Mayer, KR Gustafson - European Journal of Cancer, 2006 - Elsevier
During 2003 and 2004, marine pharmacology research directed towards the discovery and development of novel anti-tumour agents was published in 163 peer-reviewed articles. The …
JM Jimeno - Anti-Cancer Drugs, 2002 - journals.lww.com
The sea, covering 70% of the Earth's surface, offers a considerably broader spectrum of biological diversity than terra firma. Containing approximately 75% of all living organisms …
DL Dayanidhi, BC Thomas, JS Osterberg… - Frontiers in Marine …, 2021 - frontiersin.org
Marine ecosystems contain over 80% of the world's biodiversity, and many of these organisms have evolved unique adaptations enabling survival in diverse and challenging …