[HTML][HTML] B-cell activation biomarkers in salivary glands are related to lymphomagenesis in primary sjögren's disease: A pilot monocentric exploratory study

D Bruno, B Tolusso, G Lugli, C Di Mario… - International Journal of …, 2024 - mdpi.com
Primary Sjögren's disease is primarily driven by B-cell activation and is associated with a
high risk of developing non-Hodgkin's lymphoma (NHL). Over the last few decades …

[PDF][PDF] The necessity of novel biomarkers in primary Sjögren's syndrome

AG Tzioufas, AV Goules - Clin Exp Rheumatol, 2019 - clinexprheumatol.org
S-17 periepithelial inflammatory infiltrate such as B and T cells. In the era of biotechnologic
revolution, the necessity to discover novel biomarkers for pSS and define clinically useful …

Low miR200b-5p levels in minor salivary glands: a novel molecular marker predicting lymphoma development in patients with Sjögren's syndrome

EK Kapsogeorgou, A Papageorgiou… - Annals of the …, 2018 - ard.bmj.com
Objectives Development of non-Hodgkin's lymphoma (NHL) is the major adverse outcome of
Sjögren's syndrome (SS) affecting both morbidity and mortality. Preliminary evidence …

[HTML][HTML] Integrated bioinformatics and validation reveal potential biomarkers associated with progression of primary Sjögren's syndrome

N Li, L Li, M Wu, Y Li, J Yang, Y Wu, H Xu… - Frontiers in …, 2021 - frontiersin.org
Background Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease
of the exocrine glands characterized by specific pathological features. Previous studies have …

[HTML][HTML] The transcriptome of paired major and minor salivary gland tissue in patients with primary Sjögren's syndrome

GM Verstappen, L Gao, S Pringle, EA Haacke… - Frontiers in …, 2021 - frontiersin.org
Background While all salivary glands (SGs) can be involved in primary Sjögren's syndrome
(pSS), their respective role in pathogenesis remains unclear. Our objective was to assess …

[HTML][HTML] Gene expression alterations in salivary gland epithelia of Sjögren's syndrome patients are associated with clinical and histopathological manifestations

AD Cruz, V Kartha, A Tilston-Lunel, R Mi… - Scientific …, 2021 - ncbi.nlm.nih.gov
Sjögren's syndrome (SS) is a complex autoimmune disease associated with lymphocytic
infiltration and secretory dysfunction of salivary and lacrimal glands. Although the etiology of …

[HTML][HTML] Gene expression alterations in salivary gland epithelia of Sjögren's syndrome patients are associated with clinical and histopathological manifestations

A Dela Cruz, V Kartha, A Tilston-Lunel, R Mi… - Scientific Reports, 2021 - nature.com
Sjögren's syndrome (SS) is a complex autoimmune disease associated with lymphocytic
infiltration and secretory dysfunction of salivary and lacrimal glands. Although the etiology of …

Association of BAFF and IL‐17A with subphenotypes of primary Sjögren's syndrome

F Deng, J Chen, J Zheng, Y Chen… - International Journal …, 2016 - Wiley Online Library
Abstract Aim Primary Sjögren's syndrome (pSS) is an autoimmune disease affecting
exocrine glands. Both autoreactive T cells and B cells are involved in the development of …

Lymphomagenesis in Sjögren's syndrome: predictive biomarkers towards precision medicine

AV Goules, AG Tzioufas - Autoimmunity reviews, 2019 - Elsevier
Sjögren's syndrome (SS) is characterized by B cell hyperactivity documented by the
production of plethora of autoantibodies and a strong tendency for NHL of B cell origin …

[HTML][HTML] Correspondence between salivary proteomic pattern and clinical course in primary Sjögren syndrome and non-Hodgkin's lymphoma: a case report

C Baldini, L Giusti, F Ciregia, Y Da Valle… - Journal of translational …, 2011 - Springer
Background In the last years human proteomic has represented a promising tool to promote
the communication between basic and clinical science. Methods To explore the …