[HTML][HTML] Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications

IP Trougakos, K Stamatelopoulos, E Terpos… - Journal of Biomedical …, 2021 - Springer
Background Gaining further insights into SARS-CoV-2 routes of infection and the underlying
pathobiology of COVID-19 will support the design of rational treatments targeting the life …

[HTML][HTML] Pathophysiology and clinical management of coronavirus disease (COVID-19): a mini-review

Y Zhu, L Sharma, D Chang - Frontiers in Immunology, 2023 - frontiersin.org
An unprecedented global pandemic caused by a novel coronavirus named SARS-CoV-2
has created a severe healthcare threat and become one of the biggest challenges to human …

Pathophysiology of COVID-19: mechanisms underlying disease severity and progression

MK Bohn, A Hall, L Sepiashvili, B Jung… - …, 2020 - journals.physiology.org
The global epidemiology of coronavirus disease 2019 (COVID-19) suggests a wide
spectrum of clinical severity, ranging from asymptomatic to fatal. Although the clinical and …

[HTML][HTML] A cohort autopsy study defines COVID-19 systemic pathogenesis

XH Yao, T Luo, Y Shi, ZC He, R Tang, PP Zhang, J Cai… - Cell research, 2021 - nature.com
Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by
dysfunction of the lungs and extrapulmonary organs. However, the organotropism of SARS …

[HTML][HTML] Pathophysiology and treatment strategies for COVID-19

M Kumar, S Al Khodor - Journal of translational medicine, 2020 - Springer
The outbreak of Coronavirus disease of 2019 (COVID-19) caused by the Severe Acute
Respiratory Syndrome coronavirus 2 (SARS-CoV-2), has posed a serious health threat. The …

Understanding the epidemiology, pathophysiology, diagnosis and management of SARS-CoV-2

AO Fadaka, NRS Sibuyi, OB Adewale… - Journal of …, 2020 - journals.sagepub.com
The emergence of coronavirus disease 2019 (COVID-19) in December 2019 has resulted in
over 20 million cases and 741,808 deaths globally, affecting more than 200 countries …

SARS‐CoV‐2: Mechanism of infection and emerging technologies for future prospects

S Li, S Li, C Disoma, R Zheng, M Zhou… - Reviews in Medical …, 2021 - Wiley Online Library
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
spread globally to over 200 countries with more than 23 million confirmed cases and at least …

[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

[HTML][HTML] The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …

Dysregulation of cell signaling by SARS-CoV-2

RK Suryawanshi, R Koganti, A Agelidis, CD Patil… - Trends in …, 2021 - cell.com
Pathogens usurp host pathways to generate a permissive environment for their propagation.
The current spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …