Epigenetic mechanisms of gene regulation as the interface between the genome and
environment, control diverse processes in development, aging and disease. As proposed by …

Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

DNA methylation is a class of epigenetic modification essential for coordinating gene
expression timing and magnitude throughout normal brain development and for proper brain …

Over the last decade, an increasing number of reports underscored the importance of
epigenetic regulations in brain plasticity. Epigenetic elements such as readers, writers and …

DNA methylation is an epigenetic modification that spatially and temporally regulates gene
expression and has essential roles in controlling neuronal development and function. DNA …

Gene expression is modulated by epigenetic factors that come in varying forms, such as
DNA methylation, histone modifications, microRNAs, and long noncoding RNAs. Recent …

Introduction Several lines of evidence point to a key role for dynamic epigenetic changes
during brain development, maturation, and learning. DNA methylation (mC) is a stable …

Epigenetic mechanisms are essential in a host of biological processes and many different
human diseases. Epigenetic modifications include DNA methylation, histone modification …

DNA methylation compacts chromatin structure and represses gene transcription. It is
important for numerous cellular processes, including embryonic development, X …

In the mammalian genome, DNA methylation is an epigenetic mechanism involving the
transfer of a methyl group onto the C5 position of the cytosine to form 5-methylcytosine. DNA …