Epigenetics, the inheritance of genomic information independent of DNA sequence, controls
the interpretation of extracellular and intracellular signals in cell homeostasis, proliferation …

Chromatin is a macromolecular complex composed of DNA and histones that regulate gene
expression and nuclear architecture. The concerted action of DNA methylation, histone post …

Epigenetics includes a complex set of processes that alter gene activity without modifying
the DNA sequence, which ultimately determines how the genetic information common to all …

Epigenetic control of genome function is an important regulatory mechanism in diverse
processes such as lineage commitment and environmental sensing, and in disease …

The involvement of epigenetic processes in the origin and progression of cancer is now
widely appreciated. Consequently, targeting the enzymatic machinery that controls the …

Epigenetics is the study of changes in gene expression or cellular phenotype that do not
change the DNA sequence. In this review, current methods, both genomic and proteomic …

Regulation of gene expression is essential for the functioning of all eukaryotic organisms.
Understanding gene expression regulation requires determining which proteins interact with …

Histone proteins contribute to the maintenance and regulation of the dynamic chromatin
structure, to gene activation, DNA repair and many other processes in the cell nucleus. Site …

Chromatin is the macromolecular nucleoprotein complex that governs the organization of
genetic material in the nucleus of eukaryotic cells. In chromatin, DNA is packed with histone …

High‐throughput genomic sequencing and quantitative mass spectrometry (MS)‐based
proteomics technology have recently emerged as powerful tools, increasing our …