Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

J Shi, K Shiraishi, J Choi, K Matsuo, TY Chen… - Nature …, 2023 - nature.com
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain
only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage …

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Z Wang, WJ Seow, K Shiraishi… - Human molecular …, 2016 - academic.oup.com
Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women
have previously identified six susceptibility loci associated with lung cancer risk. To further …

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population

K Shiraishi, H Kunitoh, Y Daigo, A Takahashi, K Goto… - Nature …, 2012 - nature.com
Lung adenocarcinoma is the most common histological type of lung cancer, and its
incidence is increasing worldwide. To identify genetic factors influencing risk of lung …

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Q Lan, CA Hsiung, K Matsuo, YC Hong, A Seow… - Nature …, 2012 - nature.com
To identify common genetic variants that contribute to lung cancer susceptibility, we
conducted a multistage genome-wide association study of lung cancer in Asian women who …

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

J Dong, Z Hu, C Wu, H Guo, B Zhou, J Lv, D Lu… - Nature …, 2012 - nature.com
To find additional susceptibility loci for lung cancer, we tested promising associations from
our previous genome-wide association study (GWAS) of lung cancer in the Chinese …

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12. 12 and 22q12. 2 in Han Chinese

Z Hu, C Wu, Y Shi, H Guo, X Zhao, Z Yin, L Yang… - Nature …, 2011 - nature.com
Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic
factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a …

Informed Genome‐Wide Association Analysis With Family History As a Secondary Phenotype Identifies Novel Loci of Lung Cancer

JG Poirier, P Brennan, JD McKay, MR Spitz… - Genetic …, 2015 - Wiley Online Library
Lung cancer is the leading cause of cancer death worldwide. Although several genetic
variants associated with lung cancer have been identified in the past, stringent selection …

Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population

KA Zanetti, Z Wang, M Aldrich, CI Amos, WJ Blot… - Lung cancer, 2016 - Elsevier
Objectives Genome-wide association studies (GWAS) of lung cancer have identified regions
of common genetic variation with lung cancer risk in Europeans who smoke and never …

Lung cancer risk, genetic variation, and air pollution

A Urman, HD Hosgood - EBioMedicine, 2015 - thelancet.com
Large-scale multinational genome-wide association studies (GWAS) of the genetic variation
associated with lung cancer initially found that the 5p15. 33, 6p21. 33, and 15q25 regions …

A cross-tissue transcriptome-wide association study identifies novel susceptibility genes for lung cancer in Chinese populations

M Zhu, J Fan, C Zhang, J Xu, R Yin… - Human Molecular …, 2021 - academic.oup.com
Although dozens of susceptibility loci have been identified for lung cancer in genome-wide
association studies (GWASs), the susceptibility genes and underlying mechanisms remain …