ABSTRACT A substantial proportion of risk for Parkinson's disease (PD) is driven by
genetics. Progress in understanding the genetic basis of PD has been significant. So far …

Parkinson's disease is a common, progressive neurodegenerative disorder, affecting 3% of
those older than 75 years of age. Clinically, Parkinson's disease (PD) is associated with …

Abstract Knowledge regarding the pathophysiological basis of Parkinson's disease (PD) has
been greatly expanded over the past two decades, with extraordinary contributions from the …

Almost two decades after the identification of SNCA as the first causative gene in
Parkinson's disease (PD) and the subsequent understanding that genetic factors play a …

Less than a quarter century after the discovery of SNCA as the first attributable gene in
Parkinson's disease (PD), our knowledge of the genetic architecture underlying this disease …

An understanding of the genetic etiology of Parkinson disease (PD) has become imperative
for the modern-day neurologist. Although genetic forms cause only a minority of PD, the …

In the past 15 years there has been substantial progress in our understanding of the
genetics of Parkinson's disease (PD). Highly-penetrant mutations in different genes (SNCA …

There has been tremendous progress toward understanding the genetic basis of
Parkinson's disease and related movement disorders. We summarize the genetic, clinical …

Parkinson's disease (PD) is a complex and heterogeneous neurological condition
characterised mainly by bradykinesia, resting tremor, rigidity and postural instability …

The genetic landscape of Parkinson's disease (PD) is characterised by rare high penetrance
pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a …