Mucosal vitamin D signaling in inflammatory bowel disease

L Kellermann, KB Jensen, F Bergenheim, J Gubatan… - Autoimmunity …, 2020 - Elsevier
Epidemiological studies have identified vitamin D (25 (OH) D) deficiency to be highly
prevalent among patients with inflammatory bowel disease (IBD), and low serum levels …

Vitamin D signaling in intestinal innate immunity and homeostasis

V Dimitrov, JH White - Molecular and cellular endocrinology, 2017 - Elsevier
The lumen of the gut hosts a plethora of microorganisms that participate in food assimilation,
inactivation of harmful particles and in vitamin synthesis. On the other hand, enteric flora, a …

[HTML][HTML] Vitamin D and microbiome: Molecular interaction in inflammatory bowel disease pathogenesis

I Aggeletopoulou, M Marangos… - The American Journal of …, 2023 - Elsevier
Studies of systemic autoimmune diseases point to characteristic microbial patterns in
various diseases, including inflammatory bowel disease (IBD). Autoimmune diseases, and …

Molecular basis of vitamin D action in inflammatory bowel disease

C Triantos, I Aggeletopoulou, GJ Mantzaris… - Autoimmunity …, 2022 - Elsevier
There is growing evidence of vitamin D involvement in immune regulation and gut barrier
function, suggesting that vitamin D may play a critical role in the development of …

Vitamin D in inflammatory bowel diseases. Mechanisms of action and therapeutic implications

F Vernia, M Valvano, S Longo, N Cesaro, A Viscido… - Nutrients, 2022 - mdpi.com
(1) Background: Vitamin D is an immunoregulatory factor influencing intestinal homeostasis.
Recent evidence supports a central role of this micronutrient in the course of Inflammatory …

Vitamin D axis in inflammatory bowel diseases: role, current uses and future perspectives

R Del Pinto, C Ferri, F Cominelli - International journal of molecular …, 2017 - mdpi.com
Increasing evidence supports the concept that the vitamin D axis possesses
immunoregulatory functions, with vitamin D receptor (VDR) status representing the major …

Vitamin D, immune regulation, the microbiota, and inflammatory bowel disease

MT Cantorna, K McDaniel, S Bora… - Experimental biology …, 2014 - journals.sagepub.com
The inflammatory bowel diseases are complex diseases caused by environmental,
immunological, and genetic factors. Vitamin D status is low in patients with inflammatory …

Vitamin D in inflammatory bowel disease: From biology to clinical implications

SM Parizadeh, R Jafarzadeh-Esfehani… - … therapies in medicine, 2019 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of
the gastrointestinal tract consisting two principal categories, ulcerative colitis (UC) and …

Aligning the paradoxical role of vitamin D in gastrointestinal immunity

MT Cantorna, CJ Rogers, J Arora - Trends in Endocrinology & Metabolism, 2019 - cell.com
Inflammatory bowel disease (IBD) is a chronic disorder characterized by inflammation of the
gastrointestinal tract and an immune-mediated attack against the commensal microbiota …

Interplay of immunity and vitamin D: interactions and implications with current IBD therapy

J Abdo, V Rai, DK Agrawal - Current medicinal chemistry, 2017 - ingentaconnect.com
Crohn's disease (CD) and ulcerative colitis (UC) are classified under inflammatory bowel
disease (IBD) which has been linked to a multifaceted etiology involving both environmental …