We provide an in-depth review of the role of androgens in male maturation and
development, from the fetal stage through adolescence into emerging adulthood, and …

The goals of androgen therapy for adolescents are to promote linear growth and secondary
sexual characteristics, at the same time as permitting the normal accrual of muscle mass and …

Background: In adolescents, testosterone may have several effects including promotion of
secondary sexual characteristics and pubertal growth, attainment of optimal muscle mass …

In boys, the hormonal changes that accompany normal puberty are well defined, as are the
physical signs of pubertal development and the kinetics of the growth spurt. Most androgens …

During adolescence, androgens are responsible for the development of secondary sexual
characteristics, pubertal growth, and the anabolic effects on bone and muscle mass …

Testosterone replacement therapy (TRT) is routinely prescribed in adolescent males with
constitutional delay of growth and puberty (CDGP) or hypogonadism. With many new …

Male hypogonadism, the clinical syndrome with variable symptoms associated with gonadal
dysfunction, can affect men of all ages. In older males, physiologic changes of the aging …

Androgen treatment represents a main aspect of clinical management of boys with
hypogonadism from adolescence onwards. Androgen replacement therapy is required to …

During fetal development, androgens exert long-term effects which are either organizational
on specific organs during a critical phase of morphogenesis (eg sexual differentiation of …

For a long time relegated to the role of poor country cousin of female hormone replacement
therapy (HRT), androgen replacement has finally emerged as a hot topic in its own right …