Aging and Alzheimer's disease (AD) are associated with progressive brain disorganization.
Although structural asymmetry is an organizing feature of the cerebral cortex it is unknown …

Structural magnetic resonance imaging data are frequently analysed to reveal
morphological changes of the human brain in dementia. Most contemporary imaging …

Healthy aging is accompanied by progressive decline in cognitive performance and
concomitant changes in brain structure and functional architecture. Age-accompanied …

Cortical thinning occurs throughout the entire life and extends to late-life neurodegeneration,
yet the neurobiological substrates are poorly understood. Here, we used a virtual-histology …

Hemispheric asymmetry reduction in older adults (HAROLD) has been frequently reported in
studies of functional brain aging. It is commonly considered to be a plastic brain …

The human brain demonstrates structural and functional asymmetries which have
implications for ageing and mental and neurological disease development. We used a set of …

Age-related thinning of the cortical mantle varies regionally, leading to hemispheric
asymmetries in cortical thickness that may emerge at various stages of development and …

Laterality of human brain varies under healthy aging and diseased conditions. The
alterations in hemispheric asymmetry may embed distinct biomarkers linked to the disease …

Functional brain imaging studies of normal aging typically show age-related under-and
overactivations during episodic memory tasks. Older individuals also undergo nonuniform …

The intrinsic functional organization of the brain changes into older adulthood. Age
differences are observed at multiple spatial scales, from global reductions in modularity and …