Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - Nature …, 2023 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - MedRxiv, 2022 - medrxiv.org
Attention deficit hyperactivity disorder (ADHD) is a prevalent childhood psychiatric disorder,
with a major genetic component. Here we present a GWAS meta-analysis of ADHD …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

D Demontis, RK Walters, J Martin, M Mattheisen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Fitting the pieces together: current research on the genetic basis of attention-deficit/hyperactivity disorder (ADHD)

E Stergiakouli, A Thapar - Neuropsychiatric disease and treatment, 2010 - Taylor & Francis
Attention-deficit/hyperactivity disorder (ADHD) is a highly disruptive childhood-onset
disorder that often persists into adolescence and adulthood. Comorbidity with other …

Transcriptome-wide association study of attention deficit hyperactivity disorder identifies associated genes and phenotypes

C Liao, AD Laporte, D Spiegelman, F Akçimen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental psychiatric
disorder. Genome-wide association studies (GWAS) have identified several loci associated …

Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome‐wide association study of both common and …

L Yang, BM Neale, L Liu, SH Lee… - American Journal of …, 2013 - Wiley Online Library
Attention‐deficit hyperactivity disorder (ADHD) is a complex polygenic disorder. This study
aimed to discover common and rare DNA variants associated with ADHD in a large …

Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD

E Stergiakouli, M Hamshere… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: A major motivation for seeking disease-associated genetic variation is to identify
novel risk processes. Although rare copy number variants (CNVs) appear to contribute to …

[HTML][HTML] Association of polygenic risk for attention-deficit/hyperactivity disorder with co-occurring traits and disorders

E Du Rietz, J Coleman, K Glanville, SW Choi… - Biological Psychiatry …, 2018 - Elsevier
Background A recent large-scale mega genome-wide association study identified, for the
first time, genetic variants at 12 loci significantly associated with attention-deficit/hyperactivity …

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder

E Mick, A Todorov, S Smalley, X Hu, S Loo… - Journal of the American …, 2010 - Elsevier
OBJECTIVE: Genes likely play a substantial role in the etiology of attention-
deficit/hyperactivity disorder (ADHD). However, the genetic architecture of the disorder is …

The relative contribution of common and rare genetic variants to ADHD

J Martin, MC O'donovan, A Thapar, K Langley… - Translational …, 2015 - nature.com
Attention deficit hyperactivity disorder (ADHD) is highly heritable. Genome-wide molecular
studies show an increased burden of large, rare copy-number variants (CNVs) in children …