The composition of the lung microbiome is increasingly well characterised, with changes in
microbial diversity or abundance observed in association with several chronic respiratory …

Culture-independent microbiological techniques have shown a previously unappreciated
complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of …

Chronic respiratory diseases, including asthma, chronic obstructive pulmonary disease
(COPD) and cystic fibrosis (CF), are among the leading causes of mortality and morbidity …

The healthy lung has previously been considered to be a sterile organ because standard
microbiological culture techniques consistently yield negative results. However, culture …

The development of culture-independent techniques for microbiological analysis has
uncovered the previously unappreciated complexity of the bacterial microbiome at various …

The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

The lung microbiome, which is believed to be stable or at least transient in healthy people, is
now considered as a poly-microorganism component contributing to disease pathogenesis …

The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

An increasing body of evidence indicates the relevance of microbiota for pulmonary health
and disease. Independent investigations recently demonstrated that the lung harbors a …