Mast cells in the skin: defenders of integrity or offenders in inflammation?

M Voss, J Kotrba, E Gaffal… - International Journal of …, 2021 - mdpi.com
Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

[HTML][HTML] Roles of mast cells in cutaneous diseases

T Numata, K Harada, S Nakae - Frontiers in Immunology, 2022 - frontiersin.org
Mast cells are present in all vascularized tissues of the body. They are especially abundant
in tissues that are in frequent contact with the surrounding environment and act as potential …

[HTML][HTML] Mast cell functions in the innate skin immune system

M Metz, F Siebenhaar, M Maurer - Immunobiology, 2008 - Elsevier
Mast cells are not only potent effector cells in allergy, but are also important players in
protective immune responses against pathogens. Most of our knowledge about mast cells in …

The role of mast cells in the induction and maintenance of inflammation in selected skin diseases

E Woźniak, A Owczarczyk-Saczonek, M Lange… - International Journal of …, 2023 - mdpi.com
Under physiological conditions, skin mast cells play an important role as guardians that
quickly react to stimuli that disturb homeostasis. These cells efficiently support, fight …

Non‐IgE mediated mast cell activation

FA Redegeld, Y Yu, S Kumari, N Charles… - Immunological …, 2018 - Wiley Online Library
Mast cells (MC s) are innate immune cells that are scattered in tissues throughout the
organism being particularly abundant at sites exposed to the environment such as the skin …

Mast cell: an emerging partner in immune interaction

G Gri, B Frossi, F D'Inca, L Danelli, E Betto… - Frontiers in …, 2012 - frontiersin.org
Mast cells (MCs) are currently recognized as effector cells in many settings of the immune
response, including host defense, immune regulation, allergy, chronic inflammation, and …

Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity

SJ Galli, M Tsai - European journal of immunology, 2010 - Wiley Online Library
Mast cells are widely distributed in tissues, particularly near surfaces exposed to the
environment. Mast cells can be activated to secrete diverse mediators and cytokines by IgE …

Physiological roles of mast cells: collegium internationale allergologicum update 2019

G Varricchi, FW Rossi, MR Galdiero… - … Archives of Allergy and …, 2019 - karger.com
Mast cells are immune cells which have a widespread distribution in nearly all tissues.
These cells and their mediators are canonically viewed as primary effector cells in allergic …

Mast cells at mucosal frontiers

H Vliagoftis, AD Befus - Current molecular medicine, 2005 - ingentaconnect.com
Mast cells (MC) are major effector cells of IgE-mediated allergic inflammation. However, it
has become increasingly clear that they also play important roles in a diversity of …

[HTML][HTML] Mast cells as regulators of T cell responses

S Bulfone-Paus, R Bahri - Frontiers in immunology, 2015 - frontiersin.org
Mast cells (MCs) are recognized to participate in the regulation of innate and adaptive
immune responses. Owing to their strategic location at the host–environment interface, they …