The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders

C Silvestri, V Di Marzo - Cell metabolism, 2013 - cell.com
Endocannabinoids and cannabinoid CB1 receptors are known to play a generalized role in
energy homeostasis. However, clinical trials with the first generation of CB1 blockers, now …

Endocannabinoids and the control of energy balance

I Matias, V Di Marzo - Trends in Endocrinology & Metabolism, 2007 - cell.com
Two receptors have been cloned to date for the psychotropic compound Δ 9-
tetrahydrocannabinol, and termed cannabinoid CB 1 and CB 2 receptors. Their endogenous …

New insights on the role of the endocannabinoid system in the regulation of energy balance

B Gatta-Cherifi, D Cota - International journal of obesity, 2016 - nature.com
Within the past 15 years, the endocannabinoid system (ECS) has emerged as a lipid
signaling system critically involved in the regulation of energy balance, as it exerts a …

The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning?

FJ Bermudez-Silva, MP Viveros, JM McPartland… - Pharmacology …, 2010 - Elsevier
The endocannabinoid system (ECS) consists of two receptors (CB1 and CB2), several
endogenous ligands (primarily anandamide and 2-AG), and over a dozen ligand …

The therapeutic potential of targeting the peripheral endocannabinoid/CB1 receptor system

J Tam, L Hinden, A Drori, S Udi, S Azar… - European journal of …, 2018 - Elsevier
Endocannabinoids (eCBs) are internal lipid mediators recognized by the cannabinoid-1 and-
2 receptors (CB 1 R and CB 2 R, respectively), which also mediate the different …

The emerging role of the endocannabinoid system in endocrine regulation and energy balance

U Pagotto, G Marsicano, D Cota, B Lutz… - Endocrine …, 2006 - academic.oup.com
During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

The endocannabinoid system and energy metabolism

L Bellocchio, C Cervino, R Pasquali… - Journal of …, 2008 - Wiley Online Library
Many different regulatory actions have been attributed to endocannabinoids, and their
involvement in several pathophysiological conditions is under intense scrutiny. Cannabinoid …

Energy balance regulation by endocannabinoids at central and peripheral levels

C Quarta, R Mazza, S Obici, R Pasquali… - Trends in molecular …, 2011 - cell.com
Dysregulation of the endocannabinoid system (ECS) is a universal and, perhaps, causative
feature of obesity. Central nervous system (CNS) circuits that regulate food intake were …

[HTML][HTML] Endocannabinoids and the regulation of body fat: the smoke is clearing

TL Horvath - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
Endocannabinoids, endogenous ligands of cannabinoid receptor type 1 (CB1), have
emerged as novel and important regulators of energy homeostasis. A report in this issue …

The role of the endocannabinoid system in lipogenesis and fatty acid metabolism

R Vettor, C Pagano - Best practice & research Clinical endocrinology & …, 2009 - Elsevier
Endocannabinoids (ECs) regulate energy balance by modulating hypothalamic circuits
controlling food intake and energy expenditure. However, convincing evidence has …