Changes in the Gut Microbiome as Seen in Diabetes and Obesity

GM Barlow, S Celly, R Mathur - Clinical Understanding of the Human Gut …, 2024 - Springer
Diabetes rates have risen to the point where 1 in 10 adults worldwide have diabetes, and
obesity rates have more than tripled since 1975. These conditions are interrelated and …

[PDF][PDF] Microbiota and microbiome in relation to diabetes and obesity

KYG Villareal, AR Santillanes, B Lazalde - 2024 - gsconlinepress.com
Millions of microorganisms compose the human gut microbiota, essential for maintaining
metabolic health. Recent research has shown that the gut microbiome of people with obesity …

[HTML][HTML] Variations in microbial composition and function in metabolic diseases

C Greenhill - Nature Reviews Endocrinology, 2019 - nature.com
The gut microbiome is known to be dysregulated in metabolic disease. However, as obesity
and type 2 diabetes mellitus (T2DM) often occur together, teasing out the changes that are …

Gut microbiota and obesity: lessons from the microbiome

PD Cani - Briefings in functional genomics, 2013 - academic.oup.com
The distal gut harbours microbial communities that outnumber our own eukaryotic cells. The
contribution of the gut microbiota to the development of several diseases (eg obesity, type 2 …

An overview of the roles of the gut microbiome in obesity and diabetes

GM Barlow, EA Lin, R Mathur - Nutritional and therapeutic interventions for …, 2018 - Elsevier
Obesity and diabetes represent two of the most significant noncommunicable challenges in
healthcare worldwide. The gut microbiome is now known to play key roles in both of these …

Gut microbiome and type 2 diabetes: where we are and where to go?

S Sharma, P Tripathi - The Journal of nutritional biochemistry, 2019 - Elsevier
Type 2 diabetes mellitus (T2D) is a highly prevalent metabolic disorder characterized by an
imbalance in blood glucose level, altered lipid profile and high blood pressure. Genetic …

[PDF][PDF] Gut microbiome and type 2 diabetes: where we are and where to go?

S Sharmaa, P Tripathib - Journal of Nutritional Biochemistry, 2019 - innomalabs.it
Type 2 diabetes mellitus (T2D) is a highly prevalent metabolic disorder characterized by an
imbalance in blood glucose level, altered lipid profile and high blood pressure. Genetic …

The gut microbiome and type 2 diabetes mellitus: discussing a complex relationship

AK Sikalidis, A Maykish - Biomedicines, 2020 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a disease that affects over 9% of the United States
population and is closely linked to obesity. While obesity was once thought to stem from a …

[HTML][HTML] Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome

S Ussar, S Fujisaka, CR Kahn - Molecular metabolism, 2016 - Elsevier
Background Diabetes, obesity, and the metabolic syndrome are multifactorial diseases
dependent on a complex interaction of host genetics, diet, and other environmental factors …

Assessing the human gut microbiota in metabolic diseases

F Karlsson, V Tremaroli, J Nielsen, F Bäckhed - Diabetes, 2013 - Am Diabetes Assoc
Recent findings have demonstrated that the gut microbiome complements our human
genome with at least 100-fold more genes. In contrast to our Homo sapiens–derived genes …