Estimating renal function to reduce the risk of adverse drug reactions
The aging process is characterized by relevant changes in pharmacokinetics. Renal function
is known to decline with aging. However, as a result of reduced muscle mass, older …
is known to decline with aging. However, as a result of reduced muscle mass, older …
The use of estimated glomerular filtration rate for dose adjustment of medications in the elderly
CG Elinder, P Bárány, O Heimbürger - Drugs & aging, 2014 - Springer
Adverse drug effects as a consequence of inappropriate dosage are a common cause of
hospitalization among the elderly. Older individuals are at a particular risk of overdosing …
hospitalization among the elderly. Older individuals are at a particular risk of overdosing …
Comparison of estimated glomerular filtration rate with estimated creatinine clearance in the dosing of drugs requiring adjustments in elderly patients with declining …
WJ Spruill, WE Wade, HH Cobb III - The American journal of geriatric …, 2008 - Elsevier
Background: The National Kidney Foundation's practice guidelines for chronic kidney
disease recommend using the Modification of Diet in Renal Disease (MDRD) equation for …
disease recommend using the Modification of Diet in Renal Disease (MDRD) equation for …
Glomerular filtration rate equations overestimate creatinine clearance in older individuals enrolled in the Baltimore Longitudinal Study on Aging: impact on renal drug …
TC Dowling, ES Wang, L Ferrucci… - … : The Journal of Human …, 2013 - Wiley Online Library
Objectives To evaluate the performance of kidney function estimation equations and to
determine the frequency of drug dose discordance in an older population. Design Cross …
determine the frequency of drug dose discordance in an older population. Design Cross …
Reconsideration of the current models of estimated kidney function‐based drug dose adjustment in older adults: The role of biological age
R Alikhani, MP Pai - Clinical and Translational Science, 2023 - Wiley Online Library
Human lifespan has increased from a median of 46.5 years in 1950 to 71.7 years in 2022.
As people age, one of the inevitable consequences is a decline in kidney function and …
As people age, one of the inevitable consequences is a decline in kidney function and …
Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation
Background: Reduced renal function increases the risk of adverse drug reactions (ADRs) to
hydrosoluble drugs (hADRs). However, the ability of different equations to calculate …
hydrosoluble drugs (hADRs). However, the ability of different equations to calculate …
The importance of correct estimation of renal function for drug treatment in hospitalized elderly patients, especially women: a prospective observational study
A Helldén, U Bergman, I Odar-Cederlöf - Clinical Nephrology, 2019 - search.proquest.com
Aim: To compare renal function by several GFR formulas (particularly cystatin C eGFR-
“CAPA”) in relation to renal risk drugs (RRDs) in patients admitted to two geriatric wards in a …
“CAPA”) in relation to renal risk drugs (RRDs) in patients admitted to two geriatric wards in a …
Assessment of kidney function for drug dosing
AS Narva - Clinical chemistry, 2009 - academic.oup.com
The effort to improve the identification and management of patients with chronic kidney
disease (CKD) 2 is based on implementing more precise means of assessing kidney …
disease (CKD) 2 is based on implementing more precise means of assessing kidney …
Kidney function and clinical recommendations of drug dose adjustment in geriatric patients
M Karsch-Völk, E Schmid, S Wagenpfeil, K Linde… - BMC geriatrics, 2013 - Springer
Background In elderly patients chronic kidney disease often limits drug prescription. As
several equations for quick assessment of kidney function by estimating glomerular filtration …
several equations for quick assessment of kidney function by estimating glomerular filtration …
Discrepancies among equations to estimate the glomerular filtration rate for drug dosing decision making in aged patients: a cross sectional study
MM Castel-Branco, M Lavrador, AC Cabral… - International Journal of …, 2024 - Springer
Background Patients often require adjustments to drug doses due to impaired renal function.
Glomerular filtration rate (GFR) estimation using various equations can result in …
Glomerular filtration rate (GFR) estimation using various equations can result in …