Phenotypic features of cancer cachexia‐related loss of skeletal muscle mass and function: lessons from human and animal studies

A Martin, D Freyssenet - Journal of cachexia, sarcopenia and …, 2021 - Wiley Online Library
Cancer cachexia is a complex multi‐organ catabolic syndrome that reduces mobility,
increases fatigue, decreases the efficiency of therapeutic strategies, diminishes the quality of …

Cancer cachexia and skeletal muscle atrophy in clinical studies: what do we really know?

A Dolly, JF Dumas, S Servais - Journal of Cachexia …, 2020 - Wiley Online Library
Research investigators have shown a growing interest in investigating alterations underlying
skeletal muscle wasting in patients with cancer. However, skeletal muscle dysfunctions …

Molecular mechanisms of cancer cachexia‐related loss of skeletal muscle mass: data analysis from preclinical and clinical studies

A Martin, YS Gallot, D Freyssenet - Journal of Cachexia …, 2023 - Wiley Online Library
Cancer cachexia is a systemic hypoanabolic and catabolic syndrome that diminishes the
quality of life of cancer patients, decreases the efficiency of therapeutic strategies and …

Cancer cachexia is associated with a decrease in skeletal muscle mitochondrial oxidative capacities without alteration of ATP production efficiency

CM Julienne, JF Dumas, C Goupille, M Pinault… - Journal of cachexia …, 2012 - Springer
Background Cancer cachexia is a complex syndrome related to a negative energy balance
resulting in muscle wasting. Implication of muscle mitochondrial bioenergetics alterations …

Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia

MA Weber, H Krakowski-Roosen, L Schröder… - Acta …, 2009 - Taylor & Francis
Purpose. Cancer-related cachexia is an obscure syndrome leading to muscle wasting,
reduced physical fitness and quality of life. The aim of this study was to assess morphology …

[HTML][HTML] Mitochondrial dysfunction in cancer cachexia: impact on muscle health and regeneration

M Beltrà, F Pin, R Ballarò, P Costelli, F Penna - Cells, 2021 - mdpi.com
Cancer cachexia is a frequently neglected debilitating syndrome that, beyond representing a
primary cause of death and cancer therapy failure, negatively impacts on patients' quality of …

Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia–can findings from animal models be translated to humans?

TC Mueller, J Bachmann, O Prokopchuk, H Friess… - BMC cancer, 2016 - Springer
Background Cachexia is a multi-factorial, systemic syndrome that especially affects patients
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …

The influence of different muscle mass measurements on the diagnosis of cancer cachexia

S Blauwhoff‐Buskermolen, JAE Langius… - Journal of cachexia …, 2017 - Wiley Online Library
Background Progressive loss of muscle mass is a major characteristic of cancer cachexia.
Consensus definitions for cachexia provide different options to measure muscle mass. This …

Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle

N Johns, S Hatakeyama, NA Stephens, M Degen… - PloS one, 2014 - journals.plos.org
Background Cachexia affects the majority of patients with advanced cancer and is
associated with a reduction in treatment tolerance, response to therapy, and duration of …

Cancer cachexia decreases specific force and accelerates fatigue in limb muscle

BM Roberts, GS Frye, B Ahn, LF Ferreira… - … and biophysical research …, 2013 - Elsevier
Cancer cachexia is a complex metabolic syndrome that is characterized by the loss of
skeletal muscle mass and weakness, which compromises physical function, reduces quality …