The mechanism of antimicrobial activity of conjugated bile acids against lactic acid bacilli

LN Chai, H Wu, XJ Wang, LJ He, CF Guo - Microorganisms, 2023 - mdpi.com
The mechanism underlying antimicrobial activity of conjugated bile acids against strains of
lactic acid bacilli is not well understood. The purpose of this study was to investigate two …

[HTML][HTML] Effects of bile salt deconjugation by probiotic strains on the survival of antibiotic-resistant foodborne pathogens under simulated gastric conditions

X He, Y Zou, Y Cho, J Ahn - Journal of food protection, 2012 - Elsevier
This study was designed to evaluate the effects of bile acid deconjugation by probiotic
strains on the antibiotic susceptibility of antibiotic-sensitive and multiple antibiotic-resistant …

In Vitro Antibacterial Activity of Unconjugated and Conjugated Bile Salts on Staphylococcus aureus

TH Sannasiddappa, PA Lund, SR Clarke - Frontiers in Microbiology, 2017 - frontiersin.org
Bile salts are potent antimicrobial agents and are an important component of innate
defenses in the intestine, giving protection against invasive organisms. They play an …

Relationship between bile salt hydrolase activity, changes in the internal pH and tolerance to bile acids in lactic acid bacteria

AY Bustos, L Saavedra, GF de Valdez, RR Raya… - Biotechnology …, 2012 - Springer
The effect of the conjugated bile acid (BA) on the microbial internal pH (pHin) values in lactic
acid bacteria with and without ability to hydrolyze bile salts (BSH [+] and BSH [−] strains …

Bile salt hydrolase activity and resistance to toxicity of conjugated bile salts are unrelated properties in lactobacilli

SA Moser, DC Savage - Applied and Environmental Microbiology, 2001 - Am Soc Microbiol
Bacteria of numerous species isolated from the human gastrointestinal tract express bile salt
hydrolase (BSH) activity. How this activity contributes to functions of the microorganisms in …

The effect of bile salts on survival and morphology of a potential probiotic strain Lactobacillus acidophilus M92

J Šušković, B Kos, S Matošić, V Besendorfer - World Journal of …, 2000 - Springer
Bile tolerance is an important criterion in the selection of microbial strains for probiotic use.
The survival and morphological changes of a potential probiotic strain, Lactobacillus …

Bile salt deconjugation ability, bile salt hydrolase activity and cholesterol co-precipitation ability of lactobacilli strains

MT Liong, NP Shah - International Dairy Journal, 2005 - Elsevier
Eleven strains of lactobacilli were screened for their bile salt deconjugation ability, bile salt
hydrolase activity (BSH) and co-precipitation of cholesterol with deconjugated bile. Bile salt …

Bile salt deconjugation by Lactobacillus plantarum 80 and its implication for bacterial toxicity

P De Boever, W Verstraete - Journal of Applied Microbiology, 1999 - academic.oup.com
The effects of bile salts on the survival of lactobacilli were investigated using glycocholic
acid, cholic acid and deoxycholic acid as model compounds and the bile salt hydrolase …

High concentrations of conjugated bile acids inhibit bacterial growth of Clostridium perfringens and induce its extracellular cholyglycine hydrolase

M Kishinaka, A Umeda, S Kuroki - Steroids, 1994 - Elsevier
To investigate the effects of conjugated bile acid on bacterial growth and cholyglycine
hydrolase activity, Clostridium perfingens from human feces was exposed to varying …

Protective effect of the bile salt hydrolase-active Lactobacillus reuteri against bile salt cytotoxicity

P De Boever, R Wouters, L Verschaeve… - Applied microbiology …, 2000 - Springer
Bacterial bile salt hydrolysis is considered a risk factor for the development of colon cancer
because of the risk of forming harmful secondary bile salts after an initial deconjugation step …